Preface to the Third Edition Preface to the Fourth Edition Editor Biography List of Contributors 1. General Remarks on Estimating the Time Since Death Burkhard Madea and Claus Henssge 2. Historical Review on Early Work on Estimating the Time Since Death Bernard Knight and Burkhard Madea 3. Supravitality in Tissues Burkhard Madea 4. Rigor Mortis: Estimation of the Time Since Death by Evaluation of Cadaveric Rigidity Thomas Krompecher 5. Post-mortem Lividity: Hypostasis and Timing of Death Burkhard Madea and Bernard Knight 6. Post-mortem Body Cooling and Temperature-Based Methods Claus Henssge, Michael Hubig, Michal Kaliszan, Gita Mall, Holger Muggenthaler, Stefan Potente, Guy Rutty 6.1. Basics and Application of the ‘Nomogram Method’ at the Scene Claus Henssge 6.2. Finite Element Method in Temperature-Based Death Time Determination Michael Hubig, Holger Muggenthaler, Gita Mall 6.3. The Prism Method Stefan Potente 6.4. The Use of Temperatures Recorded from the External Auditory Canal for the Estimation of the Post-mortem Intervalt Guy Rutty 6.5. Eye Temperature and the Time Since Death Michal Kaliszan 7. Autolysis, Putrefactive Changes and Post-mortem Chemistry Elke Doberentz, Claus Henssge, Bernhard Knight, Burkhard Madea, Frank Musshoff, Angela Pittner, Stefan Pittner, Torleiv Ole Rognum, Brita Zilg 7. 1. Autolysis (Self-digestion) Burkhard Madea 7.2a. Eye Changes After Death Burkhard Madea and Claus Henssge 7.2b. Potassium Levels Combined with Age and Temperature Brita Zilg 7.2c. Estimation of Time Since Death Based on Vitreous Humour Hypoxanthine and Temperature Measurement Torleiv Ole Rognum 7. 3. Cerebrospinal Fluid Chemistry Burkhard Madea and Claus Henssge 7. 4. Estimation of Duration of Immersion Elke Doberentz and Burkhard Madea 7. 5. H3-Magnetic Resonance Spectroscopy Frank Musshoff and Burkhard Madea 7. 6. Post-mortem Protein Degradation Stefan Pittner and Angela Pittner 8. DNA/RNA Degradation and Time Since Death Akihiko Kimura and Toshikazu Kondo 9. Gastric Contents and Time Since Death Burkhard Madea, Bernard Knight, Elke Doberentz 10. Immunohistochemical Methods as an Aid in Estimating the Time Since Death Burkhard Madea 11. Practical Casework Claus Henssge, Burkhard Madea and Stefan Potente 11.1. Integration of Different Methods in Casework Claus Henssge and Burkhard Madea 11.2. Conditional Probability in Death Time Estimation Stefan Potente 12. Forensic Entomology Saskia Reibe 13. Radiocarbon Dating: Basic Principles and Applications Wilfried Rosendahl and Doris Döppes 14. Cross-Sectional Imaging and the Post-mortem Interval Guy Rutty 15. Drug Testing in Hair for the Estimation of the Time Since Death Christopher Wiedfeld and Frank Musshoff Index