Advanced Drug Delivery

Provides both fundamentals and new and emerging applications

Advanced Drug Delivery brings readers fully up to date with the state of the science, presenting the basics, formulation strategies, and therapeutic applications of advanced drug delivery. The book demonstrates how core concepts of pharmaceutical sciences, chemistry, and molecular biology can be combined and applied in order to spark novel ideas to design and develop advanced drug delivery systems for the treatment of a broad range of human diseases.

Advanced Drug Delivery features contributions from an international team of pharmaceutical scientists. Chapters reflect a thorough review and analysis of the literature as well as the authors' firsthand experience developing drug delivery systems. The book is divided into four parts:
* Part I, Introduction and Basics of Advanced Drug Delivery, explores physiological barriers, stability, transporters, and biomaterials in drug delivery
* Part II, Strategies for Advanced Drug Delivery, offers tested and proven strategies for advanced delivery of both small molecules and macromolecules
* Part III, Translational Research of Advanced Drug Delivery, focuses on regulatory considerations and translational applications of advanced drug delivery systems for the treatment of cardiovascular diseases, cancer, sexually transmitted diseases, ophthalmic diseases, and brain diseases
* Part IV, Future Applications of Advanced Drug Delivery in Emerging Research Areas, examines stem cell research, cell-based therapeutics, tissue engineering, and molecular imaging

Each chapter provides objectives and assessment questions to help readers grasp key concepts and assess their knowledge as they progress through the book.

Advanced Drug Delivery is recommended for graduates and upper-level undergraduates in the pharmaceutical sciences who need a solid foundation in the basics. It is also recommended for pharmaceutical professionals who want to take advantage of new and emerging applications in advanced drug delivery systems.

This book presents the essential aspects of formulation design, drug targeting, barriers present in cell level and clinical trial requirements to approve a drug delivery system. It teaches the fundamentals, practical issues, and integration of pharmaceutics and molecular biology for developing drug delivery systems. An opening section reviews basics related to physiologic barriers, transporters, and biomaterials. Then, it moves on to discuss different strategies to target both synthetic small molecules and macromolecules, and further emphasizes advanced approaches to deliver the drug in different critical and life threatening diseases such as cardiovascular, cancer, sexual transmitted, and ophthalmic diseases. The book ends by evaluating drug delivery parameters in context to present current research as well as propel the reader to consider emerging research fields like stem cell research, cell-based therapeutics, tissue engineering, and imaging. In addition, each chapter contains objectives and assessment questions.