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moss stephen j.; henley jeremy - receptor and ion-channel trafficking

Receptor and Ion-Channel Trafficking Cell Biology of Ligand-Gated and Voltage-Sensitive Ion Channels

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Dettagli

Genere:Libro
Lingua: Inglese
Pubblicazione: 08/2002





Trama

A volume in the Molecular and Cellular Neurobiology series.
This book reviews the recent advances in our understanding of the molecular and cellular mechanisms that control the assembly, transport, targeting and anchoring of the protein complexes making up the most important ion channels and receptor families, fundamental to synaptic function. Improved
understanding of these processes is expected to reveal novel therapeutic targets relevant to a range of disease states.
The first section of the book contains three chapters dealing with cation channels and provides an accessible, succinct and comprehensive account of what is known about the structures and the assembly and targeting of these multimeric proteins. The focus of the book then moves on to cover
ligand-gated ion channels with two chapters on accetylcholine receptors. The final section of the book contains four chapters covering the excitatory and inhibitory amino acid receptors.
Receptor and Ion-Channel Trafficking provides an integrated overview of the significant recent advances in the field of molecular neurobiology and will be essential reading for all researchers in neuroscience, neurobiology, biochemistry, cellular and molecular biology.




Sommario

1 - Voltage-gated sodium channels
2 - The assembly and targeting of potassium channels
3 - Assembly and targeting of voltage-dependent calcium channels
4 - Targeting of acetylcholine receptors to the postsynaptic endplate of the nerve-muscle synapse
5 - Assembly and targeting of neuronal nicotinic acetylcholine receptors
6 - AMPA/kainate receptors
7 - NMDA receptor targeting
8 - Structure, assembly and targeting of glycine receptors
9 - GABAA and GABAC receptors: regulation of assembly, localization, clustering and turnover










Altre Informazioni

ISBN:

9780192632241

Condizione: Nuovo
Collana: Molecular and Cellular Neurobiology Series
Dimensioni: 248 x 18.4 x 174 mm Ø 646 gr
Formato: Copertina rigida
Illustration Notes:numerous halftones and figures
Pagine Arabe: 236


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