Principles and Applications of Quinoproteins

Provides up-to-date information on all aspects of basic and applied research on quinoproteins and quinonoid co-factors such as pyrroloquinoline quinone (PQQ) - exploring the scope, direction and potential value of investigations in this multidisciplinary field.

Preface -- Contributors -- Part I: Introduction -- 1. A Brief History of Quinoproteins /Victor L. Davidson -- Part II: Selected Quinoproteins -- 2. Methanol Dehydrogenase in Gram-Negative Bacteria /Christopher Anthony -- 3. Bacterial Quinoproteins Glucose Dehydrogenase and Alcohol Dehydrogenase /Kazunobu Matsushita and Osao Adachi -- 4. Quinoprotein Aldehyde Dehydrogenases in Microorganisms /Kazunobu Matsushita and Osao Adachi -- 5. Methylamine Dehydrogenase /Victor L. Davidson -- 6. Copper-Containing Amine Oxidases /William S. Mclntire and Christa Hartmann -- 7. Lysyl Oxidase /Herbert M. Kagan and Philip C. Trackman -- Part III: Biosynthesis, Structure, and Function of Quinoproteins -- 8. Regulation and Expression of Bacterial Quinoproteins /Kerstin Laufer and Mary E. Lidstrom -- 9. The Role of Quinoproteins in Bacterial Energy Transduction /Christopher Anthony -- 10. X-Ray Crystallographic Studies of Quinoproteins /F. Scott Mathews and Wim G. J. Hoi -- 11. Resonance Raman Spectroscopy of Quinoproteins /David M. Dooley and Doreen E. Brown -- Part IV: Analysis and Properties of PQQ and Quinonoid Cofactors -- 12. The Chemistry of PQQ and Related Compounds /Yoshiki Ohshiro and Shinobu Itoh -- 13. Glycine-Dependent Redox Cycling and Other Methods for PQQ and Quinoprotein Detection /Rudolf Fluckiger, Mercedes A. Paz, Peter R. Bergethon, Edward Henson, and Paul M. Gallop -- 14. Biosynthesis of PQQ 343 /Clifford J. Unkefer -- 15. PQQ, A Growth-Stimulating Substance for Microorganisms /Kazunobu Matsushita and Osao Adachi -- Part V: PQQ and Quinoproteins in Medicine and Biotechnology -- 16. PQQ: Effect on Growth, Reproduction, Immune Function, and Extracellular Matrix Maturation in Mice /Francene M. Steinberg, Carsten Smidt, Jack Kilgore, Nadia Romero-Chapman, David Tran, David Bui, and Robert B. Rucker -- 17. The Biomedical Significance of PQQ /Mercedes A. Paz, Rudolf Fliickiger, and Paul M. Gallop -- 18. Pharmacological Application of PQQ /Akiharu Watanabe, Hideo Nishigori, Teizi Urakami, Toshihiro Tsuchida, and Norio Hobara -- 19. Quinoproteins as Biocatalysts /A. Netrusov -- 20. Quinoproteins as Biosensors /Isao Karube, Kenji Yokoyama, and Yasushi Kitagawa -- Index.

VICTOR L. DAVIDSON is Associate Professor, Department of Biochemistry, The University of Mississippi Medical Center, Jackson. The author or coauthor of over 60 journal articles, book chapters, and abstracts, he is a member of the American Society for Biochemistry and Molecular Biology, the American Society for Microbiology, the Biophysical Society, and the American Association for the Advancement of Science. Dr. Davidson received the B.S. degree (1973) in biochemistry from the University of Illinois at Urbana-Champaign and the Ph.D. degree (1982) in chemistry from Texas Tech University, Lubbock.