Molecular Dynamics in Biological Membranes

1 Introduction: Cell Structure and Function.- 2 Constituents of Biological Membranes.- Membrane isolation.- Membrane composition.- Membrane lipids.- Membrane proteins.- 3 Structure of Membranes and Serum Lipoprotein Complexes.- Soap molecules in aqueous solution.- Biological membranes.- Serum lipoprotein complexes.- Fluidity of membrane constituents.- Membrane action of anesthetics.- 4 Biological Consequences of Membrane Fluidity and Fusion.- Membrane biogenesis.- Intercellular junction formation.- Myogenesis.- Phagocytosis.- Secretion.- 5 Transmembrane Solute Transport Mechanisms.- Ion-transporting antibiotics.- Group translocation—the bacterial phosphotransferase system.- Group translocation—intestinal disaccharidases.- Active transport mechanisms in intestinal epithelial cells.- Energy interconversion and active transport in bacteria.- 6 Sensory Perception I: Chemoreception.- Bacterial chemoreception.- Chemotactic responses of solitary eukaryotic cells.- The chemical regulation of insect behavior.- The chemical senses of mammals.- 7 Sensory Perception II: Transmission Mechanisms.- The resting membrane potential and action potentials.- Excitability-inducing material.- Ion-conducting channels in excitable membranes.- Bioelectric control of ciliary activity in Paramecium.- Photoreception in the rod cell of the mammalian eye.- Bacterial photoreception and transmission.- 8 Hormonal Regulation of Cellular Metabolism.- The insulin receptor.- Possible mechanisms of hormone regulation.- Regulation of bacterial metabolism.- Regulation of cellular cyclic AMP levels.- 9 Cell Recognition.- Adhesion of bacteriophage to bacterial hosts.- Heterotypic adhesion—sexual agglutination in yeast.- Homotypic adhesion—sponge aggregation.- Animal cell adhesion and malignancy.- 10 Role of the Plasma Membrane in Growth Regulation and Neoplasia.- Growth of normal and transformed animal cells.- Positive growth control.- Negative growth control.- Changes in membrane structure and function associated with transformation.- Microbial systems for studying the molecular basis of neoplastic transformation.- Mammalian growth regulation and membrane biology.- Index 125.