Magnetic Nanoparticles in Biosensing and Medicine

Drawing together topics from a wide range of disciplines, this text provides a comprehensive insight into the fundamentals of magnetic biosensors and the applications of magnetic nanoparticles in medicine. Internationally renowned researchers showcase topics ranging from the basic physical principles of magnetism to the detection and manipulation, synthesis protocols and natural occurrence of magnetic nanoparticles. Up-to-date examples of their clinical usage and research applications in the biomedical fields of sensing by diverse magnetic detection methods, in imaging by MRI and in therapeutic strategies such as hyperthermia, are also discussed, providing a thorough introduction to this rapidly developing field. Each chapter features questions with answers, highlighted definition boxes, and numerous illustrations which help readers grasp key concepts. Mathematical tools, together with key literature references, provide a strong underpinning for the material, making it ideal for graduate students, lecturers, medical researchers and industrial scientific strategists.

1. Magnetism, magnetic materials and nanoparticles Adrian Ionescu, Justin Llandro and Kurt R. A. Ziebeck; 2. Preparation of magnetic nanoparticles for applications in biomedicine Pedro Tartaj, Sabino Veintemillas-Verdaguer, Teresita Gonzalez-Carreño and Carlos J. Serna; 3. Magnetic nanoparticle functionalisation Justin J. Palfreyman; 4. Manipulation Donglei Fan, Chia-Ling Chien, Thomas Schneider and Urs O. Häfeli; 5. Modeling the in-flow capture of magnetic nanoparticles Bart Hallmark, Nicholas J. Darton and D. Pearce; 6. Sensing magnetic nanoparticles Adarsh Sandhu, Paul Southern, Susana Cardoso, Simon Knudde, Filipe A. Cardoso, Paulo P. Freitas and Galina V. Kurlyandskaya; 7. Magnetic nanoparticles for MRI contrast agents Nohyun Lee and Taeghwan Hyeon; 8. Magnetotactic bacteria and magnetosomes Dennis A. Bazylinski and Denis Trubitsyn.

Nicholas J. Darton is the Technical Lead Formulation at ARECOR Ltd, where he is responsible for internal and external collaborative biopharmaceutical formulation development programs.
Adrian Ionescu is a Research Associate at the University of Cambridge. He specialises in magnetic surfaces and nanoparticles and has been awarded three Knowledge Transfer Fellowships. He currently works on quantum computing devices based on spin qubits
Justin Llandro is an Assistant Professor at Tohoku University, Japan, where he currently works on self-assembled biomimetic 3D nanostructures and ultra-small magnetic tunnel junctions for spintronics applications.