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rezaei nima (curatore); hanaei sara (curatore) - human brain and spinal cord tumors: from bench to bedside. volume 2

Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2 The Path to Bedside Management

Name: Human Brain and Spinal Cord Tumors: From Bench to Bedside. Volume 2
Price: 165,28 € EUR
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Author: Rezaei Nima (Curatore); Hanaei Sara (Curatore)
ISBN: 9783031237041

rezaei nima (curatore); hanaei sara (curatore)

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Dettagli

Genere:Libro

Lingua: Inglese

Editore:

Springer

Pubblicazione: 07/2023

Edizione: 1st ed. 2023

Trama

This book aims to gather the current knowledge regarding different aspects of brain and spinal cord tumors in order to more efficiently help the patients. Brain tumors comprise about 5–9% of all human neoplasms; and the central nervous system (CNS) neoplasms are ranked among the most prevalent neoplasms of childhood as well. The more we know about the nature and characteristic of brain and spinal cord tumors, the more precise decision could be made for each patient, in order to reach the best outcome. While surgical resection, chemotherapy, and radiotherapy have been considered as the standards of care for benign and/or malignant CNS tumors since a long time ago, new therapeutic approaches such as immunotherapy have been recently proposed to be considered for treatment of CNS tumors, especially as in some cases, the tumors might be inoperable or the patient may not benefit from other treatment modalities after several recurrences.

The second volume of the book focuses on clinical aspects of these tumors. Accordingly, the most important brain and spinal cord tumors are specifically discussed in each chapter based on a rational outlining for all chapter in this volume: Background and epidemiology, genetics, immunology and molecular biology, histopathology and morphology, imaging and radiologic features, clinical manifestations, therapeutic approaches, surgical intervention, chemotherapy and radiotherapy, new therapeutic modalities, follow-up, and prognosis. The chapters of this volume discuss the following pathologies of brain and spinal cord tumors: malignant glioma, benign glioma, meningiomas and other meningeal tumors, ependymomas, medulloblastomas, pineal tumors, choroid plexus and ventricular tumors, neuroectodermal tumors of CNS, neuroepithelial tumors of CNS, pituitary gland tumors, craniopharyngioma, schwannomas and nerve-sheet tumors, hemangioblastomas and other vascular originating tumors, brain and spinal tumors of embryonic origin, germ line cell tumors, malignant bone or cartilage-originating tumors of brain and spine, benign bone or cartilage-originating tumors of brain and spine, brain tumors affecting the orbit globe and orbit tumors affecting the brain, CNS lymphomas, metastatic lesions of the brain and spine, malignant spinal tumors, benign spinal tumors, brain and/or spinal cord tumors accompanied with other diseases or syndromes, psychological and psychiatric aspects of brain and spinal cord tumors, a brief explanation on surgical approaches for treatment of different brain tumors. This volume of book is useful for physicians of different specialties, mainly neurosurgeons, neurologists, neuropathologists, and neuroradiologists.

Sommario

Chaptre 1. Malignant Glioma

Linda M. Wang, Zachary K. Englander, Michael L. Miller, Jeffrey N. Bruce

1.1. Background and Epidemiology

1.2. Genetics, Immunology and Molecular Biology

1.3. Histopathology and Morphology

1.4. Imaging and Radiologic Features

1.5. Clinical Manifestations

1.6. Therapeutic Approaches

1.7. Follow-up and Prognosis

1.8. Conclusion

Chaptre 2. Benign Glioma

Peter B. Wu, Anna C. Filley, Michael L. Miller, Jeffrey N. Bruce

2.1. Background and Epidemiology

2.2. Genetics, Immunology and Molecular Biology

2.3. Histopathology and Morphology

2.4. Imaging and Radiologic Features

2.5. Clinical Manifestations

2.6. Therapeutic Approaches

2.7. Follow-up and Prognosis

2.8. Conclusion

Chaptre 3. Meningioma and Other Meningeal Tumors

Bailo Michele. Filippo Gagliardi, Nicola Boari, Alfio Spina, Martina Piloni, Antonella Castellano, Pietro Mortini

3.1. Background and Epidemiology

3.2. Genetics, Immunology and Molecular Biology

3.3. Histopathology and Morphology

3.4. Imaging and Radiologic Features

3.5. Clinical Manifestations

3.6. Therapeutic Approaches

3.7. Follow-up and Prognosis

3.8. Other Meningeal Tumors

3.9. Conclusion

Chaptre 4. Epondymomas in Pediatric and Adults

Marios Lampros, Nikolaos Vlachos, George A. Alexiou

4.1. Background and Epidemiology

4.2. Genetics, Immunology and Molecular Biology

4.3. Histopathology and Morphology

4.4. Imaging and Radiologic Features

4.5. Clinical Manifestations

4.6. Therapeutic Approaches

4.7. Follow-up and Prognosis

4.8. Conclusion

Chaptre 5. Medulloblastomas in Pediatric and Adults

Sergey Gorelyshev, Olga Medvedeva, Nadezhda Mazerkina, Marina Ryzhova, Olga Krotkova, Andrey V. Golanov

5.1. Background and Epidemiology

5.2. Genetics, Immunology and Molecular Biology

5.3. Histopathology and Morphology

5.4. Imaging and Radiologic Features

5.5. Clinical Manifestations

5.6. Therapeutic Approaches

5.7. Follow-up and Prognosis

5.8. Conclusion

Chaptre 6. Benign and Malignant Tumors of The Pineal Region

Pavan S. Upadhyayula, Justin A. Neira, Michael Miller, and Jeffrey N. Bruce

6.1. Background and Epidemiology

6.2. Genetics, Immunology and Molecular Biology

6.3. Histopathology and Morphology

6.4. Imaging and Radiologic Features

6.5. Clinical Manifestations

6.6. Therapeutic Approaches

6.7. Follow-up and Prognosis

6.8. Conclusion

Chaptre 7. The Tumors of Choroid Plexus and Other Ventricular Tumors

Pietro Spennato, Lucia De Martino, Carmela Russo, Maria Elena Errico, Alessia Imperato, Federica Mazio, Giovanni Miccoli, Lucia Quaglietta, Massimo Abate, Eugenio Covelli, Vittoria D'Onofrio, Giuseppe Cinalli

7.1. Background and Epidemiology

7.2. Genetics, Immunology and Molecular Biology

7.3. Histopathology and Morphology

7.4. Imaging and Radiologic Features

7.5. Clinical Manifestations

7.6. Therapeutic Approaches

7.7. Follow-up and Prognosis

7.8. Other Intraventricular Tumors

7.9. Conclusion

Chaptre 8. Embryonal Tumors of The Central Nervous System with Multilayered Rosettes and Atypical Teratoid/Rhabdoid Tumors

Margarita Kamenova, Radka Kaneva, Kamelia Genova, Nikolay Gabrovsky

8.1. Background and Epidemiology

8.2. Genetics, Immunology and Molecular Biology

8.3. Histopathology and Morphology

8.4. Imaging and Radiologic Features

8.5. Clinical Manifestations

8.6. Therapeutic Approaches

8.7. Follow-up and Prognosis

8.8. Conclusion

Chaptre 9. Glioneuronal and Neuronal Tumors of the Central Nervous System

Matteo Martinoni, Viscardo Paolo Fabbri, Emanuele La Corte, Mino Zucchelli, Sofia Asioli, Caterina Giannini

9.1. Background and Epidemiology

9.2. Genetics, Immunology and Molecular Biology

9.3. Histopathology and Morphology

9.4. Imaging and Radiologic Features

9.5. Clinical Manifestations

9.6. Therapeutic Approaches

9.7. Follow-up and Prognosis

9.8. Conclusion

Chaptre 10. Benign and Malignant Tumors of the Pituitary Gland

Luigi Albano, Marco Losa, Lina Raffaella Barzaghi, Pietro Mortini

10.1. Background and Epidemiology

10.2. Genetics, Immunology and Molecular Biology

10.3. Histopathology and Morphology

10.4. Imaging and Radiologic Features

10.5. Clinical Manifestations

10.6. Therapeutic Approaches

10.7. Follow-up and Prognosis

10.8. Conclusion

Chaptre 11. Craniopharyngioma in Pediatric and Adults

Martina Piloni, Filippo Gagliardi, Michele Bailo, Marco Losa, Nicola Boari, Alfio Spina, and Pietro Mortini.

11.1. Background and Epidemiology

11.2. Genetics, Immunology and Molecular Biology

11.3. Histopathology and Morphology

11.4. Imaging and Radiologic Features

11.5. Clinical Manifestations

11.6. Therapeutic Approaches

11.7. Follow-up and Prognosis

11.8. Conclusion

Chaptre 12. Schwannomas of Brain and Spinal Cord

Venelin Gerganov, Mihail. Petrov, Teodora Sakelarova

12.1. Background and Epidemiology

12.2. Genetics, Immunology and Molecular Biology

12.3. Histopathology and Morphology

12.4. Imaging and Radiologic Features

12.5. Clinical Manifestations

12.6. Therapeutic Approaches

12.7. Follow-up and Prognosis

12.8. Conclusion

Chaptre 13. Other Nerve-Sheet Tumors of Brain and Spinal Cord

Milhail Petrov, Teodora Sakelarova, Venelin Gerganov

13.1. Background and Epidemiology

13.2. Genetics, Immunology and Molecular Biology

13.3. Histopathology and Morphology

13.4. Imaging and Radiologic Features

13.5. Clinical Manifestations

13.6

Autore

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research and Technologies, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the Founding President of Universal Scientific Education and Research Network (USERN). Prof. Rezaei has already been the Director of more than 100 research projects and has designed and participated in several international collaborative projects. Prof. Rezaei is the editor, editorial assistant, or editorial board member of more than 40 international journals. He has edited more than 50 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,100 scientific papers in the international journals.

Dr. Sara Hanaei started medicine at TUMS in 2010 and started a master of public health (MPH) in 2014. She graduated with MD-MPH in 2018. She also received TUMS Research Diploma (TUMS-RD) in a 2-year study period from 2013-2015. She was a research assistant at Research Center for Immunodeficiencies (RCID) from 2018-2021 and further continued neurosurgery as a clinical specialty at TUMS in 2021. She has experience in teaching research skills to students.

Medical research was one of her greatest interests since the beginning of her academic education, especially in the fields of Neurosurgery and Immunology, therefore, she started research in those fields. Over the past decade, she contributed to different research projects, books, and other research activities including instructing research workshops in statistics, systematic reviews, and meta-analysis. She got involved in executive tasks and developed some executive skills through membership in the Universal Scientific Education and Research Network (USERN), where she experienced organizing scientific events, congresses, festivals, scoring, rankings, etc.