Coronary Atherosclerosis Current Management and Treatment

The prevalence of coronary artery disease is increasing due to rising rates of obesity and the fact that a greater number of people are living longer. Coronary Atherosclerosis: Current Management and Treatment addresses this leading cause of death worldwide. Atherosclerosis has a broad range of disease manifestations depending on the degree of the stenosis and the functional status of the coronary plaque. This volume, written by a leading international team of editors, addresses the pathophysiology of the disease, established and novel diagnostic approaches (both invasive and non-invasive), treatment methodologies (including treatment algorithms), and differing perspectives on treatment, including future therapies and long-term outcomes. The inclusion of personal perspectives from experts, full-color images and ancillary video files make this a key resource. Key topics include: Pharmacology of coronary artery disease (CAD) Up-to-date evidence on pathophysiology Invasive and non-invasive imaging Current evidence for risk stratification Clinical decisionmaking Coronary Atherosclerosis: Current Management and Treatment provides a state-of-the-art review of current knowledge to aid specialists, general physicians, and cardiologists in training, in the diagnosis, risk stratification, and management of patients with diverse presentations of coronary atherosclerosis.

The Pathophysiology of Coronary Atherosclerosis Current concepts of plaque formation and the progression of atherosclerosisMasataka Nakano, MD., Renu Virmani, MD., and Frank D. Kolodgie, PhDScreening and identifying the high risk individuals in the general population by using traditional risk factorsGregory Angelo Sgueglia, MD, PhD, Gaetano Antonio Lanza, MD, Filippo Crea, MDThe role of genomics and proteomics in identifying subjects at risk of clinical manifestations of coronary atherosclerosis and their future clinical applicationsCarlos L. Alviar MD, Pedro R. Moreno MDThe identification of the patient at risk using biomarkers: Current status and evolving avenues for researchGerard Pasterkamp, Imo Hoefer, Dominique de KleijnStable and unstable atherosclerotic disease: definitions, clinical manifestations and pathophysiologyJohn A Ambrose, MD FACC, Joel A. Lardizabal, MDDiagnostic Approach to Coronary Atherosclerosis: Non Invasive Approach Clinical evaluation of the patient with chest painAttilio MaseriExercise stress testing, stress echocardiography, and scintigraphy: which tool for which patient?Arend F.L. Schinkel, MD, PhD, and Manolis Bountioukos, MD, PhD, FESMultislice Computed Tomography: Role in diagnosis and risk stratificationG.J.R. ten Kate MD, MSc, K. Nieman MD, PhD, P.J. de Feyter MD, PhDMagnetic resonance imaging: Role in diagnosis and risk stratificationPier Giorgio Masci MD and Jan Bogaert MD PhDCT-PET: Role in diagnosis and potential to predict the response to revascularizationMarcelo F. di Carli, Dr. KohDiagnostic Approach to Coronary Atherosclerosis: Invasive Approach From conventional to 3-dimension coronary angiography: potential clinicalChrysafios Girasis, MDFractional flow reserve: Role in guiding clinical decision making [video content also supplied]Bernard De Bruyne, Aaron Peace, Stylianos A. PyxarasIntravascular ultrasound: Role in diagnosis and management [video content also supplied]Kenji Sakamoto MD; Yasuhiro Honda MD; Peter J. Fitzgerald MD, PhDPhotoacoustic Imaging of Coronary Arteries: current status and potential clinical applicationKrista Jansen, Gijs van Soest PhD, Ton van der Steen PhDPlaque imaging with optical coherence tomography: Current status and potential clinical implicationsFrancesco Prati, Eleonora Ficarra, Vito Ramazzotti, Mario AlbertucciThermal assessment of the human coronary atherosclerotic plaque: Current status and potential clinical implicationsKonstantinos Toutouzas, Maria Drakopoulou, Archontoula Michelongona, Eleftherios Tsiamis, Christodoulos StefanadisImaging of Structure and Composition of Lipid Core Plaque with a Combination NIRS-IVUS System: Current Status and Potential Clinical ApplicationsEmmanouil S. Brilakis, MD, PhD, Zhihua He, PhD, Stephen T. Sum, PhD, Sean P. Madden, PhD, James E. Muller, M.D.Role of Endothelial Shear Stress in the Destabilization of Coronary Plaque: Acute Coronary Syndromes and Rapid Plaque ProgressionAntonios P. Antoniadis, MD, PhD, Michail I. Papafaklis, MD, PhD, Saeko Takahashi, MD, Charles L. Feldman, ScD, Peter H. Stone, MDTissue characterization using virtual histology and iMAP: Current status and potential clinical applicationsSalvatore Brugaletta, MD; Hector M. Garcia-Garcia, MD, PhDThe role of angioscopy in the assessment of the atherosclerotic plaque: Current status and potential clinical applications [video content also supplied]Yasunori Ueda, MD, PhD; Kazuhisa Kodama, MD, PhDWhat is the optimal imaging tool for coronary atherosclerosis?Takashi Kubo, MD, PhD; Takashi Akasaka, MD, PhDTreatment methodology of coronary artery disease Optimization of primary and secondary preventionKaterina K. Naka MD, PhD, FESC, ,Aris Bechlioulis MD, Lampros K. Michalis MD, MRCP (UK), FESCAnti-ischemic pharmacotherapy in patients with established coronary artery diseaseDimitrios Alexopoulos MD, FESC, FACC, Ioanna Xanthopoulou MDAntithrombotic pharmacotherapy in patients with established coronary artery diseaseAntonio Tello-Montoliu, MD, PhD; Dominick J Angiolillo, MD, PhDInvasive assessment and management of intermediate coronary narrowingsWilliam F. Fearon, M.D.Treatment algorithm in patients with stable anginaAndrew Cassar, M.D., M.R.C.P. *Bernard J. Gersh, M.B., Ch.B., D.Phil, F.R.C.P.Treatment algorithm in patients with NSTEMI and unstable anginaFrancesco Saia, MD, PhDTreatment algorithm in patients with STEMILuca Golino MD, PhD, Giuseppe De Luca MD, PhDManagement of microvascular anginaJuan Carlos Kaski, MD, DSc, Peter Ong, MDTreatment algorithm in patients with concomitant heart valve diseaseVassilis Voudris MD FESC FACC, Panagiota Georgiadou MDTreatment approach to coronary artery disease: Diverse perspectives Clinical Perspectives on the Management of Advanced Stable Coronary DiseaseRanil de Silva PhD FRCP and Kim Fox MD FRCPInterventional Perspectives on the Management of Advanced Stable Coronary Artery Disease [video content also supplied]Joanne Shannon MD, Azeem Latib MD, Antonio Colombo MDSurgical perspectives on the Management of Advanced Stable Coronary Artery DiseaseMichael J. Mack MD, Arie Pieter Kappetein, M.D., Ph.D., Stuart Head, MSHybrid treatments and future perspectives [video content also supplied]G. Russell Reiss MD and Mathew R. Williams MDDeterminants of long term outcome following percutaneous coronary interventionPedro A. Lemos MD PhDDeterminants of long term outcome following bypass surgeryArie Pieter Kappetein, M.D., Ph.D., Stuart Head, M.BscNovel therapeutic approaches to prevention and regression of atherosclerosisKuang-Yuh Chyu, MD, PhD, Prediman K. Shah, MD

Chourmouzios Arampatzis, MD, PhD,FESC, Senior Interventional Cardiologist, Interbalkan Medical Center, Thessaloniki, Greece Eugene P. McFadden MB, BCh, BAO, DCH, MRCP(UK), FRCPI, FESC, FACC, Thoraxcenter, Erasmus University Medical Centre, Rotterdam, The Netherlands and Interventional Cardiologist, Cork University Hospital, Wilton, Cork, Ireland Lampros K. Michalis MD, Professor in Cardiology, Department of Cardiology, Medical School, University of Ioannina, Greece Renu Virmani, M.D, President and Medical Director, CVPath Institute, Inc., Gaithersburg, Maryland, USA Patrick W. Serruys MD, Head of the Interventional Dept., Heartcenter Rotterdam, Rotterdam, The Netherlands