Clinical 3D Dosimetry in Modern Radiation Therapy

This book provides a first comprehensive summary of the basic principles, instrumentation, methods, and clinical applications of three-dimensional dosimetry in modern radiation therapy treatment. The presentation reflects the major growth in the field as a result of the widespread use of more sophisticated radiotherapy approaches such as intensity-modulated radiation therapy and proton therapy, which require new 3D dosimetric techniques to determine very accurately the dose distribution. It is intended as an essential guide for those involved in the design and implementation of new treatment technology and its application in advanced radiation therapy, and will enable these readers to select the most suitable equipment and methods for their application. Chapters include numerical data, examples, and case studies.

Part I Introduction Chapter 1 Introduction and overview of the contents of the book Ben Mijnheer Chapter 2 Accuracy requirements for 3D dosimetry in contemporary radiation therapy Jacob Van Dyk, Jerry J. Battista, and Glenn S. Bauman Part II Instrumentation Chapter 3 Detectors for reference dosimetry Simon Duane and Ben Mijnheer Chapter 4 Point detectors for determining and verifying 3D dose distributions Chester Reft Chapter 5 Polymer gel dosimetry Yves De Deene Chapter 6 Radiochromic 3D detectors Mark Oldham, Titania Juang, and Suk Whan Yoon Chapter 7 Electronic Portal Imaging Device (EPID) dosimetry Boyd McCurdy, Peter Greer, and James Bedford Chapter 8 2D and semi-3D dosimetry systems Donald A. Roberts, Kelly C. Younge, and Jean M. Moran Part III Measurement and Computation Chapter 9 Small field dosimetry in photon beams Indra J Das and Paolo Francescon Chapter 10 Special delivery techniques Tomas Kron Chapter 11 4D dosimetry Emma Colvill, Jeremy Booth, and Paul Keall Chapter 12 Light-ion beam dosimetry Hugo Palmans Chapter 13 Monte Carlo applications in clinical 3D dosimetry Indrin J. Chetty and Joanna E. Cygler Chapter 14 Quantifying differences in dose distributions David Westerly and Moyed Miften Part IV Clinical Applications Chapter 15 Acceptance testing, commissioning, and QA of linear accelerators Michael Altman and Eric Klein Chapter 16 Commissioning and QA of treatment planning systems Nesrin Dogan, Ivaylo B. Mihaylov, and Matthew T. Studenski Chapter 17 Patient specific QA: pre-treatment 3D dose verification Dietmar Georg, Catharine H. Clark, and Mohammad Hussein Chapter 18 Patient specific QA: in vivo 3D dose verification Ben Mijnheer Chapter 19 Audits using end-to-end tests David S. Followill, Catharine H. Clark, and Tomas Kron Chapter 20 Brachytherapy dosimetry in three dimensions J. Adam M. Cunha, Christopher L. Deufel, and Mark J. Rivard Chapter 21 Dose outside the treatment volume in external beam therapy Stephen Kry, Rebecca Howell, and Bryan Bednarz Chapter 22 Imaging dose in radiation therapy Jonathan Sykes, Parham Alaei, and Emiliano Spezi Chapter 23 Dose verification of proton and carbon ion beam treatments Katia Parodi Part V Emerging Technological Developments Chapter 24 Dosimetry of small animal precision irradiators Frank Verhaegen and Dietmar Georg Chapter 25 3D dosimetry in synchrotron radiation therapy techniques Elke Bräuer-Krisch Chapter 26 3D dosimetry in magnetic fields Geoffrey S. Ibbott, Gye Won (Diane) Choi, Hannah Jungeun Lee, Yvonne Roed, and Zhifei Wen

Ben Mijnheer got his PhD at the University of Amsterdam on a study concerning standardization of neutron dosimetry. After working on a neutron therapy project in the Netherlands Cancer Institute (NKI) in Amsterdam, he joined this institution as a clinical physicist. Later he became Head of the Physics Department, Professor at Inholland University, and is until now involved in research projects and teaching activities at the NKI. He served for many years on the editorial board of Radiotherapy and Oncology and Medical Physics Journal, is (co-)-author of about 250 articles and chapters in books, and was supervisor of about 25 PhD theses. He was involved in the organisation of the physics programme of many international scientific meetings, and faculty member of numerous courses dealing with various aspects of radiotherapy for medical physicists, radiation oncologists and radiation therapists, both at the national and international level. He received the ESTRO Breur Gold Medal and Emmanuel van der Schueren Award.