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lópez-goñi i. (curatore); moriyón i. (curatore) - brucella

Brucella Molecular and Cellular Biology

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Dettagli

Genere:Libro
Lingua: Inglese
Pubblicazione: 11/2004
Edizione: 1° edizione





Trama

Horizon Scientific Press titles focus on high-level microbiology and molecular biology topics. Written by internationally renowned and highly respected leaders in the field, they comprise of review manuals, practical manuals, and reference texts for research scientists, bioscience professionals and graduate students.
Publication of the complete genome sequences of several different "Brucella "species has provided researchers with the opportunity to take a more directed approach to study this organism's physiology, virulence, and genetic diversity. In this book highly acclaimed "Brucella "scientists comprehensively review all of the most important advances in the "Brucella "post-genomic era providing for the first time a coherent picture of "Brucella "molecular and cellular biology.
The book opens with chapters that focus on the development of molecular diagnostic tools followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include "Brucella "comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more. Essential reading for everyone with an interest in "Brucella "and brucellosis and recommended reading for the wider body of scientists with an interest in microbial diagnostics, microbial pathogenesis, cellular microbiology and immunology, and vaccine development.




Note Editore

The book opens with chapters that focus on the development of molecular diagnostic tools and these are followed by chapters on genetic evolution and its relationship to pathogenicity. Other topics include Brucella comparative genomics and proteomics, analysis of the structure, biosynthesis and biology of glucans and lipopolysaccharides, pathogenicity, approaches to vaccine development, bacterium-host interactions, immune response, and much more. Essential reading for everyone with an interest in Brucella and brucellosis and recommended reading for the wider body of scientists with an interest in microbial diagnostics, microbial pathogenesis, cellular microbiology and immunology, and vaccine development.




Sommario

1. DNA Polymorphism and Taxonomy of Brucella Species. 2. Molecular Diagnostics of Animal Brucellosis: A Review of PCR-Based Assays and Approaches. 3. Polymerase Chain Reaction: A Powerful New Approach for the Diagnosis of Buman Brucellosis. 4. A Brucella melitensis Genomic Database. 5. Comparative Genomics of Brucella melitensis, B. suis, and B. abortus. 6. Comparative Proteomics of Brucellae species. 7. Brucella Virulence: A Matter of Control. 8. Brucella Lipopolysaccharide: Structure, Biosynthesis and Genetics. 9. Brucella Cyclic - 1,2-Glucans: Structure, Biosynthesis, Biological Activities and Role in Virulence. 10. The Brucella BvrS/BvrR and Related Two-Component Regulatory Systems of the a-2 Proteobacteria: Common Regulatory Strategies of Animal and Plant Pathogens and Endosymbionts. 11. Erythritol Metabolism and Virulence in Brucella. 12. Iron Metabolism in Brucella. 13. Brucella Interaction with Membrane Lipids of the Host Cell. 14. Invasion, Intracellular Trafficking and Replication of Brucella Organisms in Professional and Non-Professional Phagocytes. 15. The Intramacrophagic Environment of Brucella spp. and Their Replicative Niche. 16. Host Cellular Immune Responses Against Brucella spp. Evaluated Using the Mouse Model. 17. Development of New Brucella Vaccines by Molecular Methods. 18. Alternative Ovine Brucellosis Vaccine: Experiences with Drug Delivery Systems.




Autore

Ignacio Lopez-Goni, Ignacio Moriyon










Altre Informazioni

ISBN:

9781904933045

Condizione: Nuovo
Dimensioni: 9.25 x 6.25 in Ø 2.05 lb
Formato: Copertina rigida
Illustration Notes:66 b/w images and 18 tables
Pagine Arabe: 448


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