Pleural Diseases: Historic PerspectiveGian Franco Tassi and Gian Pietro MarchettiBASIC SCIENCEPleural Embryology and Gross Structure, Circulation, Lymphatics, and NervesRob J. Hallifax and Najib M. RahmanMesothelial Cells and Pleural Immunology Steven E. Mutsaers, Marie-Claude Jaurand, Y. C. Gary Lee, and Cecilia M. PrêleNormal Physiological Fluid and Cellular Contents Marc NoppenFluid and Solute Exchange in Normal and Disease States V. Courtney BroaddusPleural InflammationJason S. Zolak and Veena B. AntonyPleural Fibrosis Torry A. Tucker, Andrey A. Komissarov, Galina Florova, Sreerama Shetty, and Steven IdellGenetics of Mesothelioma Dean A. Fennell and Sara BusaccaTranscriptomics and Proteomics in Pleural Diseases Joost P. Hegmans, Lysanne A. Lievense, and Joachim G. AertsPleural Pharmacokinetics Natalia Popowicz and Brad SparlingExperimental Models: Pleural Disease Georgios T. Stathopoulos, Y.C. Gary Lee, and Bruce W.S. RobinsonCLINICAL SCIENCEApproach to Patients with Pleural Diseases Oliver Bintcliffe and Nick MaskellPleural Fluid Analysis John E. HeffnerPleural Manometry David Feller-KopmanRadiology: Diagnostic Fergus V. GleesonRadiology: Interventional Iara Maria Sequeiros and Anthony EdeyRadiology: Pleural Ultrasound Coenraad F.N. Koegelenberg and Andreas H. DiaconRadiology: Nuclear Imaging Roslyn Francis and Anna NowakPleural Histology Philip T. Cagle and Timothy Craig AllenPleural Fluid Cytology Amanda Segal, Marais Combrinck, and Siaw Ming ChaiEffusions from Cardiovascular Diseases José M. Porcel and Richard W. LightEffusion from Malignant Causes Rajesh Thomas, Ioannis Kalomenidis, James Jett, and Y.C. Gary LeeEffusions from Infections: Parapneumonic Pleural Effusion and Empyema John P. Corcoran and Najib M. RahmanEffusions from Infections: Tuberculosis Luke C. Strnad, Claudia M. Denkinger, and Madhukar PaiEffusions from Atypical Infections Lisete R. Teixeira and Francisco S. VargasEffusions Due to Lymphatic Disruption J. Terrill Huggins and Peter DoelkenEffusions in Immunocompromised Hosts Rosemary Adamson and David R. ParkEffusions from Connective Tissue Diseases Stavros Anevlavis and Demosthenes BourosEffusions Caused by Drugs Vasileios Skouras and Ioannis KalomenidisEffusions after Surgery Oner Dikensoy and Richard W. LightEffusions from Hepatic Hydrothorax José Castellote and Xavier XiolEffusions Caused by Gastrointestinal Disease David Hsia and Ali I. MusaniEffusions Associated with Gynecologic and Obstetric Conditions Benjamin C.H. Kwan and Richard W. LightOther Uncommon Pleural Effusions Craig E. Daniels and Jay H. RyuSolitary Fibrous Tumors of the Pleura Marc De Perrot and Olaf MercierUndiagnosed Pleural Effusions A. Christine Argento and Momen M. WahidiAsbestos-Related Pleural Diseases Fraser J.H. Brims and A.W. MuskMesothelioma Marc Van Lanen and Paul BaasSpontaneous Pneumothorax Paul E. Van Schil, Dragan Subotic, Chantal Vandenbroeck, Jeroen M. Hendriks, Marjan Hertoghs, and Patrick LauwersNon-Spontaneous Pneumothorax Demondes Haynes and Michael H. BaumannPleural Effusions in Pediatric Patients Esmeralda Morales and Elizabeth PerkettPleural Procedural Complications and Safety Measures Luke Garske and Claire TobinDrainage Techniques Henri ColtPleurodesis Helen E. Davies and Y.C. Gary LeeTunneled Pleural Catheters Alex Chee, Paul Maceachern, David R. Stather, and Alain TremblayMedical Thoracoscopy Pyng Lee and Philippe AstoulSurgery for Pleural Diseases Lawrence Okiror and Loic Lang-LazdunskiGene Therapy in Pleural Diseases Edmund K. Moon, Steven M. Albelda, and Daniel H. StermanSetting up a Pleural Practice Rahul Bhatnagar and Nick MaskellFuture Directions in Pleural Disease Y.C. Gary Lee and Richard W. Light