Edizione: Softcover reprint of the original 1st ed. 2003
Stroke MRI is a new imaging tool providing detailed information of the pathophysiological aspects of cerebral ischemia. This book with CD-ROM includes a case collection of 25 hyperacute stroke patients, all imaged within six hours of stroke onset with a complete stroke MRI protocol. Stroke MRI and the established clinical methods are compared and recent results from single and multicenter trials are presented to demonstrate the advantages of MRI for stroke patients. The CD-ROM contains diffusion-, T2-, T2*-perfusion-weighted images and MR angiography. Each case offers to answer the relevant questions concerning vessel status and lesion size as well as presence or absence of a "tissue at risk" with a self assessment mode and the experts’ therapeutic decision. The CD and the book are complementary to avoid redundancy as far as possible. They will be useful to both the experienced researcher using MRI and the clinician or researcher with no previous knowledge of the technology.
1 Introduction.- 2 CT as the Current Standard in Stroke Imaging.- 3 Stroke Scales.- 4 Conventional MRI, Diffusion-weighted MM (DWI) and Apparent Diffusion Coefficient (ADC).- 5 Perfusion-weighted MRI (PWI).- 6 The Penumbra and the Mismatch Concept.- 7 Stroke MRI and Intracranial Hemorrhage.- 8 Feasibility, Practicality and Logistics of a Multisequence Stroke MRI Protocol.- 9 Comparison of DWI and CT.- 10 Characterization of Hyperacute Ischemic Stroke with Stroke MRI.- 11 Thrombolytic Therapy in Stroke.- 12 Impact of Stroke MRI on Therapeutic Decision Making.- 13 Alternative and Future Imaging Prospects.- 14 The Role of Stroke MRI in Clinical Trials.- References.
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