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Pulmonary Nanomedicine Diagnostics, Imaging, and Therapeutics




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Dettagli

Genere:Libro
Lingua: Inglese
Pubblicazione: 12/2011
Edizione: 1° edizione





Note Editore

This book provides an in-depth view on engineered nanomaterials (ENM) pulmonary effects and familiarizes readers with unique aspects of nanomaterial application and research, such as the effects of physicochemical properties on cellular uptake and toxicity. It focuses on the diagnostic and therapeutic utilities of nanomaterials in different lung diseases. The book discusses the novel applications of nanotechnology for the treatment of airway diseases such as asthma, allergy, chronic obstructive pulmonary diseases, cystic fibrosis, and lung cancer. It also discusses the strategies to overcome the pathophysiological and technical barriers as an attempt to synchronize the efforts of pulmonary biologists, chemists and clinicians to develop novel nano-based diagnostics, imaging, and therapeutics tools for airway diseases.




Sommario

ContributorsPrefaceAcknowledgmentsTheranostic Applications of Nanotechnology in Chronic Obstructive Lung Diseases Neeraj Vij and Aakruti GordePulmonary Physiology and Pathogenesis of Chronic Obstructive Lung DiseasesApplication of Nano-Based Systems in Treating Chronic Obstructive Lung DiseasesNanotheranosticsMultifunctional Tumor-Targeted Nanoparticles for Lung Cancer Shinji Kuroda, Tomohisa Yokoyama, Justina O. Tam, Ailing W. Scott, Li Leo Ma, Manish Shanker, Jiankang Jin, Corbin Goerlich, David Willcutts, Jack A. Roth, Konstantin Sokolov, Keith P. Johnston, and Rajagopal RameshaIntroductionBiomarkers for Tumor TargetingNanotechnology in MedicineEGFR-Targeted Hybrid Plasmonic Magnetic Multifunctional NanoparticlesConclusionsNasal and Pulmonary Delivery of Macromolecules to Treat Respiratory and Nonrespiratory Diseases Durga Paturi, Mitesh Patel, Ranjana Mitra, and Ashim K. MitraIntroductionNasal Drug DeliveryPulmonary Drug DeliveryConclusionsIn vitro and in vivo Diagnosis of Pulmonary Disorders Using Nanotechnology Indrajit RoyIntroductionNanoparticlesIn vitro Diagnosis, Techniques, and ChallengesIn vivo Diagnosis, Challenges, and Techniques1 ALI/ARDSToxicological Studies Using NanoparticlesConclusionsNanoparticles for Targeting T Cells in Allergy and Inflammatory Airway Conditions Adham Bear, Laura B. Carpin, Conrad R. Cruz, Rebekah A. Drezek, and Aaron E. FosterIntroductionRole of T Cells in the Pathogenesis of AsthmaTreatment Strategies for AsthmaPotential T Cell–Targeted Strategies for Nanoparticle-Based TherapiesT Cell-Targeting LigandsAlternative ApproachesSummaryMultifunctional Chitosan Nanocarriers for Respiratory Disease Gene Therapy Shyam S. Mohapatra, Subhra Mohapatra, Gary Hellermann, and Rhonda R. WilburIntroductionTherapeutic Effects and Safety of Chitosan in Human DiseaseSafety and Efficacy Studies in DogsSafety of Chitosan-Gene Nanocomplexes in Nonhuman PrimatesRespiratory Disease ApplicationsFuture of ImmunotherapyConcluding RemarksTargeted Delivery to the Pulmonary Endothelium Yifei Zhang, Jiang Li, Xiang Gao, and Song LiIntroductionPulmonary Endothelium as a Target for Drug DeliveryTargeting the Pulmonary Endothelium for Imaging and Therapeutic ApplicationsConclusionNanosystems for Selective Epithelial Barrier Targeting in Chronic Airway Diseases Heather A. Parsons, Rachel L. Damico, and Venkataramana K. SidhayeIntroductionObstructive Lung DiseasesNP Delivery of Airway DiseasesToxicity of NPsConclusions and Future DirectionsPotential Respiratory Health Risks of Engineered Carbon Nanotubes James C. Bonner, Jeffrey W. Card, Stavros Garantziotis, and Darryl C. ZeldinIntroductionImmune Cell Interaction with CNTsFibrogenic Reactions to CNTsCNTs and Preexisting Allergic AsthmaCNTs and LPS-Induced Airway InflammationEffects of CNTs on Other Organ SystemsDNA Damage and Aneuploidy Caused by CNTsPleural Toxicity of CNTsConclusions










Altre Informazioni

ISBN:

9789814316484

Condizione: Nuovo
Dimensioni: 9 x 6 in Ø 1.26 lb
Formato: Copertina rigida
Illustration Notes:10 b/w images and 14 color images
Pagine Arabe: 300


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