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linington roger g.; williams philip g.; macmillan john b. - problems in organic structure determination
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Problems in Organic Structure Determination A Practical Approach to NMR Spectroscopy

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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

CRC Press

Pubblicazione: 12/2015
Edizione: 1° edizione





Note Editore

At a point where most introductory organic chemistry texts end, this problems-based workbook picks up the thread to lead students through a graduated set of 120 problems. With extensive detailed spectral data, it contains a variety of problems designed by renowned authors to develop proficiency in organic structure determination. This workbook leads you from basic problems encountered in introductory organic chemistry textbooks to highly complex natural product-based problems. It presents a concept-based learning platform, introducing key concepts sequentially and reinforcing them with problems that exemplify the complexities and underlying principles that govern each concept. The book is organized in such a way that allows you to work through the problems in order or in selections according to your experience and desired area of mastery. It also provides access to raw data files online that can be downloaded and used for data manipulation using freeware or commercial software. With its problem-centered approach, integrated use of online and digital resources, and appendices that include notes and hints, Problems in Organic Structure Determination: A Practical Approach to NMR Spectroscopy is an outstanding resource for training students and professionals in structure determination. Key Features Offers a concept-based learning platform using a graduated series of problems Presents a problem-based approach to understanding and mastery of structure determinations suitable for students and professionals Includes notes and hints to solutions in the appendices Provides access to raw data files via website for data manipulation using freeware or commercial software Ancillary materials include: A complete set of original fids for all compounds, including both 1D and 2D spectra A full color answer key Complete PDF layouts for all complex natural product problems from section 6 Condensed 1H and 13C spectra




Sommario

Structure Confirmation for Simple MoleculesStructure Confirmation for Complex MoleculesDetermination of Unknown Structures for Simple MoleculesDetermination of Unknown Structures for Complex MoleculesDetermination of Relative Configurations Using NMR MethodsComplex Unknown Natural Product Structure DeterminationAppendix A: NMR Solvent Reference Chemical ShiftsAppendix B: Problem NotesAppendix C: Problem HintsAppendix D: Distribution of Experiment TypesAppendix E: Distribution of Functional GroupsAppendix F: Selected 15N NMR Chemical Shifts




Autore

Roger G. Linington, PhD, is a Tier II Canada Research Chair in Chemical Biology and High-Throughput Screening in the Department of Chemistry at Simon Fraser University, Burnaby, British Columbia, Canada. He earned his PhD from the University of British Columbia. His postdoctoral research was a joint appointment between the University of California San Diego and the Smithsonian Tropical Research Institute, which gave him the opportunity to participate in an international neglected disease drug discovery program in Panama City, Panama. He was also a faculty member in the Department of Chemistry and Biochemistry at the University of California Santa Cruz for eight years.Philip G. Williams, PhD, caught the spectroscopy bug as a summer research student at the University of Calgary while working on a series of alkaloids from African plants. He earned his PhD at the University of Hawaii at Manoa. He did his postdoctoral work at the Scripps Institution of Oceanography in San Diego on microbial natural products before returning to the University of Hawaii at Manoa as a faculty member. His research interests are natural products and their applications in the fields of cancer and neurological diseases.John B. MacMillan, PhD, is a faculty member at the University of Texas Southwestern Medical Center. He earned his PhD at the University of California Davis, where his interests in small molecule NMR began by studying the natural products chemistry of marine organisms. He did his postdoctoral work at the Scripps Institution of Oceanography in San Diego with microbial natural products. His research focuses on the chemical and biological characterization of natural products with therapeutic potential in the areas of oncology and infectious disease.










Altre Informazioni

ISBN:

9781498719629

Condizione: Nuovo
Dimensioni: 11 x 8.5 in Ø 4.80 lb
Formato: Brossura
Pagine Arabe: 755
Pagine Romane: xvi


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