Pharmacology

Since 1975, the Oklahoma Notes have been among the most widely used reviews for medical students preparing for Step 1 of the United States Medical Licensing Examination. Completely revised and updated, these new editions of the Notes feature: More self- assessment questions, geared to the current USMLE format; more tables and figures to promote rapid self-assessment and review; low prices; and coverage of just the information needed to ensure Boards success.

1 General Principles.- Mechanisms of Drug Action.- Absorption of Drugs.- Distribution of Drugs.- Excretion of Drugs.- Determinants of Plasma Concentrations and Dosage Schedules.- Metabolism of Drugs.- Pharmacogenetics.- Review Questions.- 2 Drugs Acting on the Peripheral Nervous System.- Autonomic Nervous System: Parasympathetic Division (Cholinergic).- Autonomic Nervous System: Ganglia.- Somatic Nervous System: Neuromuscular Blocking Drugs.- Autonomic Nervous System: Sympathetic Division (Adrenergic).- Review Questions.- 3 Drugs Acting on the Kidney.- Diuretics.- Antidiuretic Drugs.- Review Questions.- 4 Drugs Acting on the Cardiovascular System.- Calcium Entry Blockers.- Antianginal Drugs.- Antiarrhythmic Drugs.- Therapy of Congestive Heart Failure.- Therapy of Hyperlipoproteinemias.- Antihypertensive Therapy.- Review Questions.- 5 Drugs Affecting Hemostasis and Hematopoiesis.- Drugs Which Affect Blood Coagulation.- Anti-anemia Drugs (Hematinics).- Review Questions.- 6 Drugs Acting on the Central Nervous System.- Anesthesic Agents.- General Anesthetics.- Local Anesthetics.- Pain Relief.- Opioid Agonists.- Opioid Antagonists.- Mixed Agonists/Antagonists.- Anti-migraine Drugs.- Sedative-Hypnotics.- Benzodiazepines.- Barbiturates.- Other Agents.- Alcohols.- Neurologic Drugs.- Antiepileptic Drugs.- Antiparkinsonism Drugs.- CNS Muscle Relaxants.- Psychopharmacologic Drugs.- Central Nervous System Stimulants.- Antidepressants and Lithium.- Obsessive Compulsive Disorder.- Antipsychotics.- Drugs of Abuse.- Review Questions.- 7 Autacoids and the Therapy of Inflammation.- Autacoids.- Histamine and Antihistamines.- Serotonin and Serotonin Antagonists.- Bradykinin.- Angiotensin.- Prostaglandins (and Related Agents).- Non-Steroidal Anti-Inflammatory Drugs (NSAIDS).- Miscellaneous Agents for the Treatment of Rheumatoid Arthritis.- Miscellaneous Agents for the Treatment of Gout.- Review Questions.- 8 The Endocrine System.- Thyroid-Antithyroid.- Adrenocortical Steroids.- Parathyroid Hormone and Other Factors Affecting Bone Metabolism.- Insulin.- Ovarian Hormones and Ovulatory Agents.- Androgens and Anabolic Steroids.- Anterior Pituitary and Hypothalamus.- Posterior Pituitary Hormones.- Review Questions.- 9 Anti-Infective Agents.- to Chemotherapy.- Chemotherapy of Microbial Diseases.- Beta-Lactam Antibiotics.- Vancomycin.- Macrolide Antibiotics.- Lincomycin and Clindamycin.- Chloramphenicol.- Tetracyclines.- Aminoglycosides.- Fluoroquinolones.- Sulfonamides.- Urinary Antiseptics.- Miscellaneous Antibacterial Drugs.- Antifungal Agents.- Antiviral Agents.- Antiseptics and Disinfectants.- Review Questions.- 10 Cancer Chemotherapy and Immunosuppressive Agents.- Cancer Chemotherapy.- Immunosuppressive Agents.- Review Questions.- 11 Chemotherapy of Parasitic Diseases.- Protozoan Infections.- Metazoan Infections.- Review Questions.- 12 Gastrointestinal Drugs.- Upper GI Disorders.- Lower GI Disorders.- Review Questions.- 13 Respiratory Drugs.- Drugs Used for Asthma.- Other Respiratory Disorders.- Review Questions.- 14 Drugs Acting on the Uterus.- Oxytocic Drugs.- Uterine Relaxants (Tocolytic Drugs).- Review Questions.- 15 Toxicology.- Emergency Treatment of the Poisoned Patient.- Heavy Metals.- Metal Chelating Agents.- Teratogenesis.- Chemical Carcinogenesis.- Review Questions.- 16 Vitamins.- Water Soluble Vitamins.- Fat Soluble Vitamins.- Review Questions.- 17 U.S. Drug Laws.- Drug Laws.- Review Questions.- Annotated Answers to Review Questions.- 1 General Principles.- 2 Drugs Acting on the Peripheral Nervous System.- 3 Drugs Acting on the Kidney.- 4 Drugs Acting on the Cardiovascular System.- 5 Drugs Affecting Hemostasis and Hematopoiesis.- 6 Drugs Acting on the Central Nervous System.- 7 Autacoids and the Therapy of Inflammation.- 8 The Endocrine System.- 9 Anti-Infective Agents.- 10 Cancer Chemotherapy and Immunosuppressive Agents.- 11 Chemotherapy of Parasitic Diseases.- 12 Gastrointestinal Drugs.- 13 Respiratory Drugs.- 14 Drugs Acting on the Uterus.- 15 Toxicology.- 16 Vitamins.- 17 U.S. Drug Laws.