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emma francesco (curatore); goldstein stuart l. (curatore); bagga arvind (curatore); bates carlton m. (curatore); shroff rukshana (curatore) - pediatric nephrology

Pediatric Nephrology

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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

Springer

Pubblicazione: 09/2022
Edizione: 8th ed. 2022





Trama

Over the course of the previous seven editions, Pediatric Nephrology has become the standard reference text for students, trainees, practicing physicians (pediatricians, nephrologists, internists, and urologists), subspecialists, and allied health professionals seeking information about children’s kidney diseases. It is global in perspective, reflecting the fact that the international group of editors are all acknowledged world experts. 

The latest edition of this text is no different, providing a comprehensive, state-of-the-art overview on pediatric nephrology. Much like the previous edition, the latest edition reviews the most critical aspects of the field. Topics covered include developmental physiology and diseases, renal physiology and diagnostic approaches, glomerular disease, kidney involvement in systemic diseases, renal tubular disorders, homeostasis, cystic kidney disease and related disorders, urinary tract disorders, hypertension, acute kidney injury, and chronic kidney failure.

Unlike the previous edition, however, the chapters in this edition now combine physiology, clinical management, and pathology for ease of use. The latest edition also includes a new section on the evaluation of different disorders that can have multiple etiologies, setting the stage for the evaluation and management of specific diseases. 

This book serves as a superb resource and an invaluable asset for practitioners, health professionals, and trainees seeking out information about children's kidney diseases. 





Sommario

Pre-natal development of the kidneys and urinary tract.- Post-natal renal maturation.- Congenital abnormalities of the kidneys and the urinary tract.- Stem cells and kidney regeneration.- Assessment of kidney function.- Imaging kidneys and the urinary tract.- Technical aspects of renal pathology.- Approach to the child with hematuria and/or proteinuria.- Nephrotic syndrome: classification and evaluation.- Genetic bases of nephrotic syndrome.- Congenital nephrotic syndrome.- Clinical aspects of genetic forms of nephrotic syndrome.- Inherited diseases of the glomerular basement membrane.- Steroid sensitive nephrotic syndrome.- Non-genetic forms of steroid resistant nephrotic syndrome.- Membranous nephropathy.- Evaluation of children with nephritic syndrome.- IgA Nephropathy.- Henoch Schönlein Purpura Nephritis.- Renal vasculitis.- Lupus nephritis.- Autoantibodies and kidney diseases.- C3 glomerulopathies.- Atypical HUS and TTP.- Infection-related HUS.- Acute post-streptococcus glomerulonephritis.- Infections that affect the kidney (non-viral).- Viral infections and the kidney.- The kidney in sickle cell disease.- The kidney in type I diabetes.- The kidney in metabolic syndrome.- Renal Manifestations of Metabolic Disorders.- The kidney in methyl malonic acidemia.- The kidney in mitochondrial cytopathies.- Fabry disease.- Primary hyperoxaluria.- Fanconi Syndrome.- Cystinosis.- Aminoaciduria and Glycosuria.- Renal hypophosphatemia.- Inherited disorders of sodium and potassium handling.- Inherited disorders of renal magnesium handling.- Inherited disorders of renal calcium handling.- Renal Tubular Acidosis.- Inherited disorders of water handling.- Tubulointerstitial nephritis.- Sodium and Water Disorders: evaluation and management.- Potassium disorders: evaluation and management.- Clinical use of diuretics.- Autosomal Dominant Polycystic Kidney Diseases.- Autosomal Recessive Polycystic Kidney Diseases.- Renal involvement in tuberous sclerosis.- Nephronophtisis and other ciliopathies.- Autosomal Dominant Tubulointerstitial Kidney Diseases.- Urolithiasis and nephrocalcinosis.- Urinary tract infections.- Vesicoureteral reflux.- Obstructive uropathies.- Bladder disorders.- Enuresis.- Pediatric renal tumors.- Onconephrology.- Pathophysiology and epidemiology of hypertension in children.- Evaluation and management of hypertension.- Renovascular hypertension: evaluation and management.- Pathogenesis of acute kidney injury.- Evaluation and management of acute kidney injury in neonates.- Evaluation and management of acute kidney injury in children.- Nephrotoxins.- Progression of chronic kidney disease and nephroprotection.- Epidemiology and management of Chronic Kidney Disease.- Nutrition, Growth and Development.- CKD-MBD.- Anemia in CKD.- Assessment of volume status in CKD.- Peritoneal Dialysis.- Hemodialysis.- Infant dialysis.- Adequacy of dialysis.- Renal Transplantation: Evaluation of children and donors.- Renal transplantation: surgical and perioperative management.- Renal transplantation: immunosuppression.- Renal transplantation: disease recurrence.-  Renal transplantation: infectious complications.- Renal transplantation: non- infectious complications and long-term outcome.- Multi-organ transplants and the kidney in other solid organ transplantation.- Ethical issues in pediatric nephrology.- Drug dosing in abnormal kidney functions in Children with Abnormal Renal Function.- Normal reference values.




Autore

Francesco Emma, MD
Bambino Gesù Children’s Hospital – IRCCS
Division of Nephrology
Rome, Italy

Stuart L. Goldstein, MD
Director, Center for Acute Care Nephrology 
Medical Director, Pheresis Service
Co-Director, Heart Institute Research Core
Cincinnati Children's Hospital Medical Center
Division of Nephrology and Hypertension
Cincinnati, OH
USA

Arvind Bagga, MD
All India Institute of Medical Sciences
Division of Nephrology
Ansari Nagar, New Delhi
India

Carlton M. Bates, MD
Chief, Division of Pediatric Nephrology
Children’s Hospital of Pittsburgh 
University of Pittsburgh Medical Centerr
Pittsburgh, PA
USA

Rukshana Shroff, MD, FRCPCH, PhD
Great Ormond Street Hospital for Children
NHS Foundation Trust
London, UK

Dr. Emma received his Medical Degree and specialized in Pediatrics from the Catholic University of Louvain, Brussels, Belgium. He then completed his training in Pediatric Nephrology at Boston Children's Hospital, Harvard Medical School. In 1998, Dr. Emma moved to the Bambino Gesù Children's Hospital - IRCCS, in Rome, where he has set-up the Nephrology Research Laboratory and was appointed Chief of the Division of Pediatric Nephrology in 2005. He currently holds the position of Head of the Department of Pediatric Subspecialties.

Dr. Emma has authored more than 160 research articles in peer-reviewed journals and is the author of several textbook chapters and one of the editors of the Pediatric Nephrology textbook. He is the chair of the ESPN (European Society of Pediatric Nephrology) Working Group on Inherited Renal Disorders. His primary research interests are in rare renal diseases, in particular cystinosis and idiopathic nephrotic syndrome.

Stuart L. Goldstein, MD, has been an active investigator in the field of pediatric acute kidney injury (AKI) since 2000. Dr. Goldstein’s main research foci include: AKI epidemiology and outcomes, acute renal replacement therapy provision and investigation of novel urinary AKI biomarkers in the pediatric population. Dr. Goldstein has established a strong record of interdisciplinary and inter-institutional collaboration with cardiologists, intensivists and emergency center physicians, which is evidenced by his establishment and directing of the Prospective Pediatric Continuous Renal Replacement Therapy Registry from 2001 to 2012, and the Prospective Pediatric AKI Research Group (ppAKI-RG) in 2012. The ppAKI-RG is comprised of 52 centers from around the world with the goal of improving outcomes for the child with or at-risk for, AKI.

Carl Bates, MD, has had a career as a clinical pediatric nephrologist and basic research scientist for over 15 years. Dr. Bates was recruited to Children’s Hospital of Pittsburgh of UPMC and the University of Pittsburgh School of Medicine in 2008, where he is currently Professor of Pediatrics, Cell Biology and Developmental Biology; Vice Chair of Basic Research in Pediatrics, Division Chief of Pediatric Nephrology; and co-Director of the Pediatric Nephrology Fellowship Training Program.

In addition to caring for children with pediatric kidney disease for many years, Dr. Bates has had an internationally-recognized research program focused on genetic regulation of kidney and bladder development, with more than 15 years of continuous funding by the National Institutes of Health. His mouse models of kidney and bladder disease have helped us understand many of the structural kidney and bladder birth defects seen in children, which make up the most frequent causes of kidney disease in children.

Dr. Shroff is a Consultant Pediatric Nephrologist at Great Ormond Street Hospital and looks after children with chronic kidney disease (CKD) and those on dialysis.

Dr. Shroff’s PhD and current research focus on cardiovascular disease in children with CKD, with particular emphasis on identifying and reducing the burden of modifiable risk factors in dialysis patients. She has supervised 3 MSc students and currently co-supervises 2 PhD students.

She says "I hope that my approach through ‘translational’ (bench-to-bedside) research will improve the lives of dialysis patients by reducing their risks of heart disease and bone problems".

She has published widely in her field and written educational reviews and book chapters.

Dr. Shroff is an associate editor for Pediatric Nephrology, the main journal in the field.










Altre Informazioni

ISBN:

9783030527181

Condizione: Nuovo
Dimensioni: 254 x 178 mm
Formato: Copertina rigida
Illustration Notes:XXVIII, 2134 p. 339 illus., 260 illus. in color. In 2 volumes, not available separately.
Pagine Arabe: 2134
Pagine Romane: xxviii


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