NMR in the Life Sciences

Special Problems of NMR in H2O Solution.- 2D NMR with Biopolymers.- Proton Assignment Strategies in Nucleic Acid NMR Studies.- Genetic Methods in High-REsolution NMR Studies of Proteins.- Determination of Macromolecular Structure and Dynamics by NMR.- NMR Studies of Protein-Ligand Interactions: Dihydrofolate Reductase.- Diversity of Molecular Recognition: The Combining Sites of Monoclonal Anti Spin Label Antibodies.- NMR Approaches to the Characterization of the Interaction of Metal Ions with Proteins.- Volume Selection Strategies for In Vivo Biological Spectroscopy.- The Use of Nuclear Magnetic Resonance Rotating Frame Experiments for One Dimensional Discrimination of Metabolites in Tissues.- Proton-NMR of Nuclei, Cell and Intact Tissue in Normal and Abnormal States: Significance of Relaxation Times as Correlated with Other Non-Invasive Biophysical Probes.- Towards NMR Spectroscopy In Vivo: The Use of Models.- Towards NMR Spectroscopy In Vivo: II. Relationship between NMR Parameters and Histology.- Theory of NMR Imaging.- Some Observations of NMR Imaging Particularly in Lower Fields.- Signal, Noise and R. F. Power in Magnetic Resonance Imaging.- High Field NMR Imaging and Spectroscopy.