Neuroimmune Diseases From Cells to the Living Brain

1. Overview of mechanisms underlying neuroimmune diseases.- 2. Roles of interleukines in neurological autoimmunity.- 3. Roles of regulatory T cells in neurological autoimmunity.- 4.Immune tolerance triggering neurological autoimmunity.- 5. Disruption of blood-brain barrier and blood-nerve barrier: a key step in development of immune-mediated neurological diseases.- 6. Pathological mechanisms underlying production of autoantibodies.- 7. Significance of autoantibodies: cause or result?.- 8. Multiple actions of microglia.- 9.  Autoimmune astropathy.- 10. Genetic factors indicating susceptibility to neurological diseases.- 11. General principles of immunotherapy.- 12. Multiple sclerosis.- 13. Neuromyelitis optica: Diagnosis and therapies.- 14. Atypical inflammatory demyelinating syndrome.- 15. Central nervous system vasculitis.- 16. Neuro-Beçhet and Sjogren disease.- 17. Immune-mediated cortical encephalopathy (Limbic encephalitis).- 18.  Immune-mediated cerebellar ataxias.- 19. Stiff-Person syndrome.- 20. Guillain-Barré syndrome.- 21. Chronic inflammatory demyelinating polyneuropathy: Diagnosis and therapy.- 22.  Immune-mediated disorders of neuro-muscular junctions.- 23. Myositis.- 24. Infection-related immune diseases.- 25. Paraneoplastic neurological syndromes; Diagnosis and Therapies.

Hiroshi Mitoma is Neurologist and Neurophysiologist , Professor and Chairman, Medical Education Promotion Center and Department Medical Education at Tokyo Medical University. 

Mario Manto is Neurologist, Head of the Department of Neurology at the CHU-Charleroi, Professor of Neuroanatomy and Neurological Semiology at the University of Mons. He is also teaching Pathophysiology of the Nervous System. He is the Founding Editor of The Cerebellum, Cerebellum and Ataxias and has written or edited 10 books.