NanoCellBiology Multimodal Imaging in Biology and Medicine

This book provides a comprehensive understanding of the discovery of a new cellular structure the "porosome," which is the universal secretory machinery in cells; the protein assembly, biomineralization, and biomolecular interactions; the molecular evolution of protein structure; the use of magnetic nanoparticles for transformative application in medicine and therapy, and the new and novel imaging approach of electrical impedance spectroscopy in biology. It be used for college courses in nanomedicine, nano cell biology, advanced nanotechnology, and biotechnology at the undergraduate and graduate level.

Porosomes -The Universal Secretory Portals In Cells: A Brief EssayThe Hair Cell Porosome: Molecular and Synaptic ImplicationsThe Neuronal Porosome Complex in Mammalian Brain: A Study Using Electron MicroscopyGranule Size Distribution Suggests Mechanism: The Case for Granule Growth and Elimination as a Fusion Nano-MachineProbing Protein Assembly, Biomineralization, and Biomolecular Interactions by Atomic Force MicroscopyHigh-Resolution Imaging of Amylin Aggregation and Internalization in Pancreatic Cells: Implications in Health and DiseaserRepair of Nanodefects in a 2-Dimensional Crystal Anticoagulant Shield in the Antiphospholipid Syndrome: Novel Molecular Strategies Assessed by Atomic Force MicroscopyA novel approach to study molecular evolution: Detection of ancestral conformation hidden in present-day proteins using antibody as nanostructure probesmRNA Nanomachines and Stress Reprogramming Following Brain Ischemia. Physical Properties and Biomedical Applications of Superparamagnetic Iron Oxide NanoparticlesAtomic Force Microscopy Imaging of DNA Delivery Nano-systemsImpedance Spectroscopy for Characterization of Biological FunctionsIndex.

Bhanu P. Jena is George E. Palade University Professor and distinguished professor, Department of Physiology, Wayne State University School of Medicine, USA, and director of the NanoBioScience Institute at the university. He received his PhD from Iowa State University followed by postdoctoral studies and faculty positions at Yale University School of Medicine prior to his current position. Douglas J. Taatjes is professor of pathology and director of the Microscopy Imaging Center in the College of Medicine, University of Vermont, USA. He received his PhD from the Biocenter, University of Basel, Switzerland, prior to his current position.