Nanobiosensors and Nanobioanalyses

This book provides a comprehensive review of established, cutting-edge, and future trends in the exponentially growing field of nanomaterials and their applications in biosensors and bioanalyses. Part I focuses on the key principles and transduction approaches, reviewing the timeline featuring the important historical milestones in the development and application of nanomaterials in biosensors and bioanalyses. Part II reviews various architectures used in nanobiosensing designs focusing on nanowires, one- and two-dimensional nanostructures, and plasmonic nanobiosensors with interferometric reflectance imaging. Commonly used nanomaterials, functionalization of the nanomaterials, and development of nanobioelectronics are discussed in detail in Part III with examples from screen-printed electrodes, nanocarbon films, and semiconductor quantum dots. Part IV reviews the current applications of carbon nanotubes, nanoneedles, plasmonic sensors, electrochemical scanning microscopes, and field-effect transistors with the future outlook for emerging technologies. Attention is also given to potential challenges, in particular, of taking these technologies at the point-of-need. The book concludes by providing a condensed summary of the contents, with emphasis on future directions.

Nanomaterials have become an essential part of biosensors and bioanalyses in the detection and monitoring of medical, pharmaceutical, and environmental conditions, from cancer to chemical warfare agents. This book, with its distinguished editors and international team of expert contributors, will be an essential guide for all those involved in the research, design, development, and application of nanomaterials in biosensors and bioanalyses.

Preface.- Part I Introduction to Nanobiosensors and Nanobioanalyses.- 1 Nanobiosensors and Nanobioanalyses: A Review (Mun’delanji C. Vestergaard and Eiichi Tamiya).- Part II Nanobiosensing Architectures.- 2 Vertically Aligned Nanowire Arrays Based Sensors and its Catalytic Applications (Kafil M. Razeeb, Mamun Jamal, Maksudul Hasan, and Alan Mathewson).- 3 Device Architecture and Biosensing Applications for Attractive One- and Two-Dimensional Nanostructures (Chun-Da Liao, Tien-Chun Tsai, Yi-Ying Lu, and Yit-Tsong Chen).- 4 Nanoimprinted Plasmonic Biosensors and Biochips (Keiichiro Yamanaka and Masato Saito).- 5 Nanoparticle Biosensing With Interferometric Reflectance Imaging (Derin Sevenler, Nese Lortlar Ünlü, and M Selim Ünlü).- Part III Nanomaterial Functionalization and Nanobioelectronics.- 6 Nanomaterial-based Dual Detection Platforms: Optics Meets Electrochemistry (Nan Li and Kagan Kerman).- 7 Nanocarbon Film Based Electrochemical Detectors and Biosensors (Osamu Niwa and Dai Kato).- 8 Hybrid Metallic Nanoparticles: Enhanced Bioanalysis and Biosensing via Carbon Nanotubes, Graphene, and Organic Conjugation (Michael A. Daniele, Maria Pedrero, Stephanie Burrs, Prachee Chaturvedi, Wan Wardatul Amani Wan Salim, Filiz Kuralay, Susana Campuzano-Ruiz, Eric McLamore, and Jonathan C. Claussen).- 9 Novel Nanobiosensing Using a Focused Laser Beam (Hiroyuki Yoshikawa).- 10 Semiconductor Quantum Dots and Energy Transfer for Optical Sensing and Bioanalysis: Principles (Miao Wu and W. Russ Algar).- 11 Semiconductor Quantum Dots and Energy Transfer for Optical Sensing and Bioanalysis: Applications (Miao Wu and W. Russ Algar).- 12 Nanoparticles-based Detection of Protein Phosphorylations (Sanela Martic and Heinz-Bernhard Kraatz).- Part IV Applications, Challenges, and Future Outlook.- 13 Carbon Nanotubes: Advances, Integration, and Applications to Printable Electrode Based Biosensors (Vinci Wing Sze Hung and Kagan Kerman).- 14 Specialized Nanoneedles for Intracellular Analysis (Ryuzo Kawamura, Yaron R. Silberberg, and Chikashi Nakamura).- 15 Plasmonic Sensors for Analysis of Proteins and an Oncologic Drug in Human Serum (Jean-Francois Masson and Sandy Shuo Zhao).- 16 Scanning Electrochemical Microscopy for Imaging Single Cells and Biomolecules (Yasufumi Takahashi, Hitoshi Shiku, and Tomokazu Matsue).- 17 Field-effect transistors: current advances and challenges in bringing them at point-of-care (Shrey Pathak and Pedro Estrela).- BM Concluding Remarks.- Index.