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ameta keshav lalit (curatore); kant ravi (curatore); penoni andrea (curatore); maspero angelo (curatore); scapinello luca (curatore) - n-heterocycles

N-Heterocycles Synthesis and Biological Evaluation

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Lingua: Inglese


Pubblicazione: 04/2022
Edizione: 1st ed. 2022


This book presents an overview of the recent advancements for the synthesis of small- and medium-sized azaheterocycles, including pyrroles, indoles, pyrimidines, pyridines, pyrrolidines, imidazoles, pyrazoles, pyrazolines, lactams, and 1,2,3-triazoles, which are significant scaffolds for compounds with pharmaceutical uses. The book also discusses various properties and performance attributes of azaheterocycles including their bioactivity and synthetic strategies. Given the contents, the book will be a valuable reference for students, researchers, and professionals interested in organic synthesis and medicinal chemistry.


Pyridines, Dihydropyridines and Piperidines: An Outline on Synthesis and Biological Activities.- Imidazole, Hydantoins, Thiazole, and Oxazole: A Journey on Synthetic and Biological Relevance.- Lactams, Azetidines, Penicillins, and Cephalosporins: An Overview on the Synthesis and their Antibacterial Activity.- Synthesis and Biological importance of Pyrazole, Pyrazoline, and Indazole as Antibacterial, Antifungal, Antitubercular, Anticancer and Anti-inflammatory Agents.- An overview on the Synthesis and Biological Studies of Some Seven Membered Heterocyclic Systems.- Various Synthetic Strategies and Therapeutic Potential of Thiadiazole, Oxadiazole, Isoxazole and Isothiazole Derivatives.- Sulfur-Containing Pyrazoles, Pyrazolines and indazoles.- Synthetic Approach of Quinazolines Candidates.- An overview of Cinnolines, Quinazolines and Quinoxalines: Synthesis and Pharmacological Significance.- Pharmacological Significance of Triazoles and Tetrazoles in Neurodegenerative Disease: An Overview.- An Insight into the Synthesis and Pharmacological Activities of Indoles, Isoindoles and Carbazoles.- Pyrazoles, Indazoles and Pyrazolines : Recent Developments and their Properties.- Synthesis of Bioactive Thioxoimidazolidinones, Oxazolidinones, Thioxothiazolidinones, Thiazolidinediones.


Prof. (Dr.) Keshav Lalit Ameta is working as a Professor and Head at the Department of Chemistry, School of Liberal Arts and Sciences, Mody University of Science and Technology, Lakshmangarh, Rajasthan, India. His fields of research are green chemistry and nanotechnology in organic synthesis, heterocyclic and medicinal chemistry. In addition, to this he has keen interests in photocatalysis. Prof. Ameta has published over 80 research articles in the field of synthetic organic chemistry, medicinal chemistry, and material science with publishers of international repute. Moreover, he is honored Fellow of Linnean Society of Chemistry (FLS) UK in 2021 and Fellow of Indian Chemical Society in 2014. He has vast experience of teaching both graduate and postgraduate level students. Apart from this, he is faculty advisor of American Chemical Society (ACS) chapter and Research and Development coordinator at SLAS, Mody University of Science and Technology.

Dr. Ravi Kant, FRSC(UK), FICS, FLS(UK), presently working as Professor of Chemistry, Faculty of Chemical Sciences with an additional Responsibility of Director Research and Consultancy, Shri Ramswaroop Memorial University Lucknow-Deva Road Uttar Pradesh India. From past 21 years, involved in Research in the area of bioorganometallics, material science and metalopharmaceutical chemistry along with teaching of Chemistry/Applied Chemistry/Pharmaceutical and Medicinal Chemistry in undergraduate and post graduate students of engineering, science and pharmaceutical sciences. He is the winner of Rashtriya Shiksha Gaurav Puraskar-2015, Young Scientist Award-2018, and Best Faculty Award-2017 along with many more scientific recognition from across the country. He is an active fellow of Royal Society of Chemistry London, Linnean Society of London, Indian Science Congress Association, Uttar Pradesh Academy of Sciences, Indian Chemical Society, Chemical Research Society of India and Centre for Educational Growth & Research. 

Andrea Penoni is Associate Professor in Organic Chemistry at the Department of Science and High Technology at the University of Insubria in Como, Italy since 2017. He graduated in Chemistry (1996, laurea degree) and received a PhD in Chemical Sciences (2000, doctoral research) at the University Statale of Milano under the supervision of Professor Sergio Cenini working on a project on amination reaction of olefins and hydrocarbons using transition metal complexes as catalysts. He did his postdoctoral training at the University Statale of Milano, and then joined the research group of Professor Kenneth M. Nicholas (2000–2001) at the University of Oklahoma, where he studied the annulation reactions between nitro- and nitrosoaromatics with alkynes. Since 2003, he has been Assistant Professor in Organic Chemistry at the University of Insubria and worked in the research group of Professor Giovanni Palmisano. His research is particularly focused on the synthesis of nitrogen-containing heterocycles, naturally occurring compounds and potentially bioactive molecules. Further, he is involved in research projects on the carbon–nitrogen bond formation mediated by metals and metal complexes and synthesis of biindole compounds as interesting moieties in material science. 

Angelo Maspero is Associate Professor in Inorganic Chemistry at the Department of Science and High Technology at the University of Insubria in Como, Italy since 2017. His research interests involve Coordination and Organometallic Chemistry (working on the Synthesis, Reactivity and Spectroscopic characterization), Homogeneous Catalysis studying the Molecular dioxygen reactivity, the Oxidation and oxygenation of organic substrates, Carbon dioxide activation and functionalization, Catalytic formation of C-C, C-N and C-O bonds. He worked even on Organic synthesis assisted by metal centers: Polymerization and olygomerization of alkynes, Cyclopropanation of alkenes. His recent research works in Inorganic Materials (Synthesis and spectroscopic characterization of coordination polymers, Photoluminescent properties of coordination compounds). In the last decade he particularly focused his attention on the preparation, characterization and study of the properties of Metal-Organic Frameworks). 

Luca Scapinello got his Chemistry BS and MSc in 2017 under the supervision of prof. A. Penoni at the Department of Science and High Technology in University of Insubria and he is currently working as PhD student in the same group. His research topics focus on novel strategies for indole ring synthesis and, in cooperation with prof. T. Benincori, on synthesis of inherently chiral biindoles for applications in materials science. He spent 10 months as visiting PhD student at University of Stuttgart (Germany) in the Polymer Chemistry group headed by prof. S. Ludwigs.

Altre Informazioni



Condizione: Nuovo
Dimensioni: 235 x 155 mm Ø 875 gr
Formato: Copertina rigida
Illustration Notes:XIII, 459 p. 767 illus., 187 illus. in color.
Pagine Arabe: 459
Pagine Romane: xiii

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