Molecular Tools and Infectious Disease Epidemiology

The application of modern molecular genetic and biologic techniques to infectious disease epidemiology dramatically improves measurement of disease and putative risk factors increasing our ability to detect and track outbreaks, identify risk factors and detect new infectious agents. However, integration of these techniques into epidemiologic studies also poses new challenges in the design, conduct, and analysis. We examine these opportunities and methodologic challenges giving specific examples. The book will be written for the reader with limited understanding of genetics, biology and epidemiology.

*Presents the key points of consideration when integrating molecular biology and epidemiology

*Discusses how using molecular tools in epidemiologic research affects program design and conduct

*Considers the ethical concerns that arise in molecular epidemiologic studies

*Provides a context for understanding and interpreting scientific literature as a foundation for subsequent practical experience in the laboratory and in the field

 

Dr. Betsy Foxman is the Hunein F. and Hilda Maassab Professor of Epidemiology, Director of the Center for Molecular and Clinical Epidemiology of Infectious Diseases (MAC-EPID), Director of the Integrated Training in Microbial Systems (ITiMS) program, and Director of the Certificate Program in Healthcare Associated Infection Prevention and Control (CHIP) at the University of Michigan. Foxman received her Bachelor of Science in Conservation of Natural Resources from the University of California, Berkeley, and MSPH and PhD in Epidemiology from the UCLA School of Public Health. Foxman studies the transmission, pathogenesis, ecology, and evolution of infectious agents with an emphasis on transmission. Current research projects include studies of the interactions between viral infections and microbiota, vaginal microbiota and pre-term birth, the oral microbiota and dental health, and epidemiology of antibiotic resistant bacteria.