Mild Cognitive Impairment International Perspectives

The Classic Edition of this foundational text includes a new preface from Holly A. Tuokko, examining how the field of Mild Cognitive Impairment (MCI) has developed since first publication. Bringing together research from multiple studies and perspectives from various countries, the volume identifies MCI as an important clinical transition between normal aging and the early stages of Alzheimer's disease (AD). The up-to-date preface highlights the expansion in research, examining the benefits of various pharmacological, cognitive and behavioral approaches to intervention. Influenced by recent findings in neuroplasticity across the lifespan, the book recognizes the importance of intervention at the earliest stages of the decline trajectory. It revisits the contested diagnostic approaches for MCI as well as the varying prevalence of MCI internationally, yet points to the need for further longitudinal studies to fully understand the condition. Mild Cognitive Impairment continues to provide a comprehensive resource for clinicians, researchers and students involved in the study, diagnosis, treatment and rehabilitation of people with MCI.

About the editors List of contributors From the series editor Introduction to the Classic Edition Part I Introduction An overview of mild cognitive impairment HOLLY A. TUOKKO AND IAN MCDOWELL Part II General Population Research on MCI 2 The PAQUID study COLETTE FABRIGOULE, PASCALE BARBERGER-GATEAU, AND JEAN-FRANÇOIS DARTIGUES 3 Cognitive impairment in elderly persons without dementia: Findings from the Kungsholmen Project KATIE PALMER, LARS BACKMAN, BRENT J. SMALL, AND LAURA FRATIGLIONI 4 Population levels of mild cognitive impairment in England and Wales JANE FLEMING, FIONA E. MATTHEWS, MARK CHATFIELD, AND CAROL BRAYNE 5 The Melbourne Aging Study ALEXANDER COLLIE, PAUL MARUFF, DAVID G. DARBY, COLIN MASTERS, AND JON CURRIE Part III Specific Samples 6 Mild cognitive impairment in the Religious Orders Study ROBERT S. WILSON, NEELUM T. AGGARWAL, AND DAVID A. BENNETT 7 A perspective from the Mayo Clinic GLENN SMITH, MARY MACHULDA, AND KEJAL KANTARCI 8 Prediction of probable Alzheimer's disease: The Sunnybrook Memory Study MARY C. TIERNEY 9 Studies in the Leipzig Memory Clinic: Contribution to the concept of mild cognitive impairment HENRIKE WOLF AND HERMANN-JOSEF GERTZ Part IV Interventions 10 Emerging pharmacological therapies for mild cognitive impairment HOWARD CHERTKOW 11 Cognition-based therapies and mild cognitive impairment ROBERT T. WOODS AND LINDA CLARE 12 Combined therapies in mild cognitive impairment KEVIN PETERS AND GORDON WINOCUR Part V Summary and Future Directions 13 The future of mild cognitive impairment HOLLY A. TUOKKO AND DAVID F. HULTSCH Author index Subject index

Holly A. Tuokko was a Professor in the Department of Psychology and Institute on Aging and Lifelong Health at the University of Victoria. She was awarded Senior Investigator status through the Canadian Institutes of Health Research, Institute of Aging (2002–2007), for her program of research on mental health and aging. David F. Hultsch was a Professor of Psychology at the University of Victoria from 1984 onward, with a major research focus on cognition and aging. He was a founder of the journal Aging, Neuropsychology, and Cognition, serving as co-editor for 10 years.