Herbs for Diabetes and Neurological Disease Management Research and Advancements

This new volume provides a plethora of new information about potential medicinal herbs and their usefulness in treating diabetes and neurological diseases. Most large multinational companies are interested and engaged in the commercialization of herb-based formulations, and consumers continue to seek natural-based therapies. Herbs for Diabetes and Neurological Disease Management provides insight into plant-based novel molecules targeted for diabetes and neurological disorders. It looks at a selection of herbs that have proven effective in the management of diabetes and neurological disorders, including migraine, epilepsy, memory disorders, depression, and more. Divided into ten chapters focusing on diabetes and its macro- and microvascular complications (migraine, epilepsy, memory disorders, depression and other neuropsychiatric disorders), this book is structured to provide a source of reliable information and enrich the knowledge of readers. Each chapter briefly explains the epidemiology and pathophysiology of the disease state and the possible role of herbal drugs in the prevention of the particular disease. The reported pharmacological activities and possible mechanism of action of herbal drugs are also discussed in detail, which makes this book informative and unique.This new volume will be a reliable reference complementing the substantial information on the use of herbal drugs in diabetes and neurological disorders that serve as the pillars of drug discovery and development.

Role of St.-John’s Wort (Hypericum perforatum L.) in the Management of Diabetes and Neurological DisordersYusuf Ozturk, Ozgur Devrim Can, and Umide Demir-OzkayA Potential Natural Product Combination Targeting Memory DisordersManju Bhaskar, Meena Chintamaneni, and Veeranjaneyulu AddepalliPhytotherapeutic Agents in EpilepsyAlka BaliHerbal Medicines in Neuropsychiatric Illness: The Case of L-StepholidineNitin Sati, Kedar S. Prabhavalkar, Sridhar N., and Lokesh K. BhattPotential of Curcuma longa and Withania Somnifera for Diabetes and Associated Neurological ComorbiditiesSuruchi Verma, Amitabha Dey, and Vikas KumarMigraine: Management and Treatment with Herbal DrugsD. K. Arulmozhi, Yogesh A. Kulkarni, Addepalli Veeranjaneyulu, and R. S. GaudComplications of Diabetes and Role of a Citrus Flavonoid Nobiletin in Its TreatmentL. K. Bhatt, N. A. Parkar, V. Addepalli, and R. S. GaudDiabetes and Phytopharmaceuticals: Translational Pharmacology PerspectivePriyanka Ingle-Jadhav, Trupti R. Angolkar, and Ginpreet KaurNatural Products as Effective Treatment Option for DepressionYogesh A. Kulkarni, Kalyani H. Barve, and Ginpreet KaurMedicinal Plants ResearchMila Emerald and David Marrero

Vikas Kumar, PhD, is currently working in research and product development at the National Center for Natural Products Research (NCNPR), School of Pharmacy, at the University of Mississippi. He was formerly an Innovation Specialist at DD Innovations, Inc., Edina, Minnesota, USA, and Associate Professor of Pharmacology at the Neuropharmacology Research Laboratory, Department of Pharmaceutics, at the Indian Institute of Technology (Banaras Hindu University) in Uttar Pradesh, India. He has published more than 150 papers in peer-reviewed journals as well as four books and eight book chapters. He has visited Canada, Germany, France, China, Nepal, Thailand, Singapore, South Africa, Italy and UAE to enhance his professional experience at various capacities. He is life member of several professional associations and serves as a member of editorial boards of many peer-reviewed international journals. He previously worked successfully and productively in the pharmaceutical industries viz. Lupin Research Park, Pune, and Indian Herbs Research & Supply Co. Ltd., Saharanpur, India. Based on his research findings, Indian Herbs Ltd. successfully launched a product viz. MoodOn® (as a herbal antidepressant and mood enhancer) into the Indian market in collaboration with Bergen Healthcare, a division of Alkem Laboratories Ltd., Mumbai. Currently, MoodOn® is sold under trade name EnMood® (http://www.indianherbs.org/mEnMood.htm). He also has scientific collaborations with Dr. Willmar Schwabe GmbH & Co. KG, Germany. Dr. Kumar has received Sami Khatib Gold Medal for being a topper in B.Pharm. and Servier Young Investigators’ Award instituted by Institutet de Researches Internationales Servier, France. He is also recipient of the coveted institutional and globally reputed Rashtriya Gaurav Award in 2011 for his achievements in the field of science and technology. Dr. Kumar has obtained his PhD degree from IIT (BHU), Varanasi in 2001 after completing MPharm and BPharm from Gulbarga University in 1997 and 1995 respectively.Addepalli Veeranjaneyulu, PhD, is presently serving as Associate Dean and Senior Professor and Head of Pharmacology at SPP, the School of Pharmacy and Technology Management (SPTM), NMIMS, Mumbai, India. He was formerly a Visiting Scientist/Professor at the International Institute of Medical Sciences in China (from 2006-07) under the auspices of Canadian Heart Foundations. Dr. Addepalli has 16 years of industrial new drug discovery research experience, with over six years as Assistant Director (Pharmacology and Quality Assurance) at NCER, at Lupin Research Park, Pune, India, and over ten years as Research Executive (Pharmacology and Pharmacokinetics) in IDPL R&D, Hyderabad, India. He has 18 years of teaching experience. His research interests are cardiovascular dysfunction and other complications in diabetes; receptor pharmacology; serotonergic receptors; and modulatory roles in migraine, psychosis, and other CNS disorders. He was the Principal Investigator for several projects funded by CSIR, UGC, AICTE, and pharma industrial/academia collaborative projects funded by various pharma companies. He is a member of several national and international professional bodies and is an editorial board member and reviewer for several journals journals. Dr. Addepalli has over 180 research publications in national and international journals with three industrial patents to his credit. He also presented papers at international and national conferences and seminars and also chaired scientific sessions.