Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues

Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues analyzes trends in non-invasive glucose sensing and their impact on tissue optical properties. The book presents research on glucose metabolism in physiological norm and pathology, coherent and polarization properties of light scattered by tissues, and biological fluids containing glucose on physiological and hyper-physiological levels. It addresses the commercialization of glucose sensors and describes glucose-induced optical clearing effects in tissue and blood. The author also covers new optical techniques for glucose diffusion and sensing based on light scattering, coherent-domain, polarization-sensitive, and optoacoustic measurements.

Although noninvasive, continuous monitoring of glucose concentration in blood and tissues is one of the most challenging areas in medicine, a wide range of optical techniques has recently been designed to help develop robust noninvasive methods for glucose sensing. For the first time in book form, the Handbook of Optical Sensing of Glucose in Biological Fluids and Tissues analyzes trends in noninvasive optical glucose sensing and discusses its impact on tissue optical properties. This handbook presents methods that improve the accuracy in glucose prediction based on infrared absorption spectroscopy, recent studies on the influence of acute hyperglycemia on cerebral blood flow, and the correlation between diabetes and the thermo-optical response of human skin. It examines skin glucose monitoring by near-infrared spectroscopy (NIR), fluorescence-based glucose biosensors, and a photonic crystal contact lens sensor. The contributors also explore problems of polarimetric glucose sensing in transparent and turbid tissues as well as offer a high-resolution optical technique for noninvasive, continuous, and accurate blood glucose monitoring and glucose diffusion measurement. Written by world-renowned experts in biomedical optics and biophotonics, this book gives a complete, state-of-the-art treatise on the design and applications of noninvasive optical methods and instruments for glucose sensing.

Preface Glucose: Physiological Norm and Pathology Lidia I. Malinova and Tatyana P. Denisova Commercial Biosensors for Diabetes Vasiliki Fragkou and Anthony P.F. Turner Monte Carlo Simulation of Light Propagation in Human Tissues and Noninvasive Glucose Sensing Andrey V. Bykov, Mikhail Yu. Kirillin, and Alexander V. Priezzhev Statistical Analysis for Glucose Prediction in Blood Samples by Infrared Spectroscopy Gilwon Yoon Near-Infrared Reflection Spectroscopy for Noninvasive Monitoring of Glucose—Established and Novel Strategies for Multivariate Calibration H. Michael Heise, Peter Lampen, and Ralf Marbach Characterizing the Influence of Acute Hyperglycaemia on Cerebral Hemodynamics by Optical Imaging Qingming Luo, Zhen Wang, Weihua Luo, and Pengcheng Li Near-Infrared Thermo-Optical Response of the Localized Reflectance of Diabetic and Non-Diabetic Human Skin Omar S. Khalil In Vivo Nondestructive Measurement of Blood Glucose by Near-Infrared Diffuse-Reflectance Spectroscopy Yukihiro Ozaki, Hideyuki Shinzawa, Katsuhiko Maruo, Yi Ping Du, and Sumaporn Kasemsumran Glucose Correlation with Light Scattering Patterns Ilya Fine Challenges and Countermeasures in NIR Noninvasive Blood Glucose Monitoring Kexin Xu and Ruikang K. Wang Fluorescence-Based Glucose Biosensors Gerard L. Cotè, M. McShane, and M.V. Pishko Quantitative Biological Raman Spectroscopy Wei-Chuan Shih, Kate L. Bechtel, and Michael S. Feld Tear Fluid Photonic Crystal Contact Lens Noninvasive Glucose Sensors Sanford A. Asher and Justin T. Baca Pulsed Photoacoustic Techniques and Glucose Determination in Human Blood and Tissue Risto Myllylä, Zuomin Zhao, and Matti Kinnunen A Noninvasive Glucose Sensor Based on Polarimetric Measurements through the Aqueous Humor of the Eye Gerard L. Cotè and Brent D. Cameron Noninvasive Measurements of Glucose in the Human Body Using Polarimetry and Brewster Reflection off of the Eye Lens Luigi Rovati and Rafat R. Ansari Toward Noninvasive Glucose Sensing Using Polarization Analysis of Multiply Scattered Light Michael F.G. Wood, Nirmalya Ghosh, Xinxin Guo, and I. Alex Vitkin Noninvasive Monitoring of Glucose Concentration with Optical Coherence Tomography Rinat O. Esenaliev and Donald S. Prough Measurement of Glucose Diffusion Coefficients in Human Tissues Alexey N. Bashkatov, Elina A. Genina, and Valery V. Tuchin Monitoring of Glucose Diffusion in Epithelial Tissues with Optical Coherence Tomography Kirill V. Larin and Valery V. Tuchin Glucose-Induced Optical Clearing Effects in Tissues and Blood Elina A. Genina, Alexey N. Bashkatov, and Valery V. Tuchin Index