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bawa raj (curatore); audette gerald f. (curatore); reese brian (curatore) - handbook of clinical nanomedicine

Handbook of Clinical Nanomedicine Law, Business, Regulation, Safety, and Risk

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Genere:Libro
Lingua: Inglese
Editore:

Pan Stanford

Pubblicazione: 06/2016
Edizione: 1° edizione





Note Editore

This unique handbook (60 chapters) examines the entire "product life cycle," from the creation of nanomedical products to their final market introduction. While focusing on critical issues relevant to nanoproduct development and translational activities, it tackles topics such as regulatory science, patent law, FDA law, ethics, personalized medicine, risk analysis, toxicology, nano-characterization and commercialization activities. A separate section provides fascinating perspectives and editorials from leading experts in this complex interdisciplinary field.





Sommario

LAW, BUSINESS, AND COMMERCIALIZATION

An Intellectual Property Primer for Nanomedical Researchers and Engineers
Brian E. Reese, JD, PhD, MBA

Strategic Intellectual Property Management: Building IP Portfolios
Jeffery P. Langer, PhD, JD

Extending Patent Term for Nanomedical Inventions: A Nexus between the FDA and the Patent System
Susanne M. Hopkins, JD, and Ari G. Zytcer, JD

When Patented Technologies Get Put to Experimental Use: Practical Considerations for Nanotech R&D
Victor H. Polk, Jr, JD, and Roman Fayerberg, JD

Bridging Diagnostics Research, Development and Commercialization
Rosanna W. Peeling, PhD

What the Supreme Court’s Myriad Decision Means for Nanotechnology Patents
Andrew S. Baluch, JD, Stephen B. Maebius, JD, and Harold C. Wegner, JD

Managing the Expense of Patent Litigation in Nanotechnology
Todd G. Vare, JD

Technology Transfer: An Overview
Bruce D. Goldstein, JD, MS

Licensing Issues in Nanotechnology
Joanna T. Brougher, JD, MPh

Commercializing Your Intellectual Property: Steps to Take and Pitfalls to Avoid
Inna Dahlin, PhD, JD, and Michael J. Pomianek, PhD, JD

Overcoming Nanotechnology Commercialisation Challenges: Case Studies of Nanotechnology Ventures
Elicia Maine, PhD

The Commercialisation of Nanotechnology: The Five Critical Success Factors to a Nanotech-Enabled Whole Product
Craig Belcher, MBA, PhD, Richard Marshall, MBA, Grant Edwards, PhD, and Darren Martin, PhD

Overcoming the Odds: How to Incubate Fledging Bioscience Companies
Patti Breedlove, MS

Market Opportunity for Molecular Diagnostics in Personalized Cancer Therapy
Elemer Piros, PhD, Istvan Petak, MD, PhD, Attila Erdos, MD, John Hautman, JD, and Julianna Lisziewicz, Ph

Nanotechnology Implications for Labor
Noela Invernizzi, PhD, and Guillermo Foladori, PhD

Insurance Market Perception of Nanotechnology and Nanomaterials Risks
Lijana Baublyte, PhD, Martin Mullins, PhD, Finbarr Murphy, PhD, and Syed A.M. Tofail, PhD

REGULATORY ISSUES AND NANOGOVERNANCE

FDA and Nano: Baby Steps, Regulatory Uncertainty and the Bumpy Road Ahead|
Raj Bawa, MS, PhD

EU Regulation of Nanobiotechnology
John Quinn, LLM

Regulating Nanomedicine
Shannon G. Fischer, MS

Nanomedicines: Addressing the Scientific and Regulatory Gap
Sally Tinkle, PhD, Scott E. McNeil, PhD, Stefan Mühlebach, PhD, Raj Bawa, MS, PhD, Gerrit Borchard, PhD, Yechezkel Barenholz, PhD, Lawrence Tamarkin, PhD, and Neil Desai, MS, PhD

Regulation of Combination Products in the United States
John Barlow Weiner, JD, and Thinh X. Nguyen

Regulation of Combination Products in the European Union
Janine Jamieson, PhD, and Elizabeth Baker

Brief Overview of Current Developments in Nanotechnology EHS Regulation in the U.S.
Theodore Voorhees, Jr., JD

EPA Targets Nanotechnology: Hi-Ho, Nanosilver, Away?
David L. Wallace, JD, and Justin A. Schenck, JD

Graphene: Regulatory Considerations for the "Wonder Material"
Matthew Kaplan, JD, and Jennifer Woloschyn, JD

The Enduring Embrace: The Regulatory Ancien Régime and Governance of Nanomaterials in the U.S.
Christopher Bosso, PhD

HEALTH, SAFETY, RISK, AND BIOLOGICAL INTERACTIONS

Safety of Engineered Nanomaterials and Occupational Health and Safety Issues for Commercial-Scale Production
Paul F. A. Wright, PhD, and Neale R. C. Jackson, PhD

Engineered Nanoparticle Release, Exposure Pathway and Dose, Measures and Measuring Techniques for Nanoparticle Exposure in Air
Heinz Fißan, PhD, and Hans-Georg Horn, PhD

Managing Environmental and Health Risks in the Nanotechnology Industry
Joseph Luke Huan, LLB (Hons), MPhil

Risk Perception and Risk Communication on the Issue of Nanotechnology
Gaby-Fleur Böl, PhD, Guido Correia Carreira, PhD, Astrid Epp, PhD, Eva Häffner, PhD, and Mark Lohmann, PhD

In vitro Risk Assessment of Nanoparticles
Birgit K. Gaiser, Julia Susewind, Nadia Ucciferri, Eva-Maria Collnot, Arti Ahluwalia, and Vicki Stone

Biological Responses to Nanoparticles
Reinhard Zellner, PhD, Julia Blechinger, PhD, Cristoph Bräuchle, PhD, I. Hilger, Andreas Janshoff, PhD, Juergen Lademann, PhD, Volker Mailänder, PhD, Martina C. Meinke, PhD, G. U. Nienhaus, PhD, A. Patzelt, MD, F. Rancan, Barbara Rothen-Rutishauser, PhD, Roland H. Stauber, PhD, A. A. Torrano, PhD, Lennart Treuel, PhD, and A. Vogt

Cell and Protein Interactions with Diamond
Roger J. Narayan, MD, PhD, R. D. Boehm, BS, and Nancy A. Monteiro-Riviere, PhD

Intracellular Transport and Unpacking of Polyplex Nanoparticles
Andrey A. Rosenkranz, PhD, Yuri V. Khramtsov, PhD, Alexey V. Ulasov, PhD, Nikita Rodichenko, and Alexander S. Sobolev, DSci, PhD

Complement Activation: A Capricious Immune Barrier to the Clinical Use of Nanomedicines
János Szebeni, MD, PhD, DSc

Nanotoxicology: Focus on Nanomedicine
Helinor Johnston, PhD, Ali Kermanizadeh, PhD, and Vicki Stone, PhD

Toxicity and Genotoxicity of Metal and Metal Oxide Nanomaterials: A General Introduction
Mercedes Rey, David Sanz, and Sergio E. Moya

Toxicity of Silicon Dioxide Nanoparticles in Mammalian Neural Cells
James C. K. Lai, PhD, Ashvin R. Jaiswal, MS, Maria B. Lai, MS, Sirisha Jandhyam, MS, Solomon W. Leung, PhD, and Alok Bhushan, PhD

FUTURE IMPLICATIONS, ETHICS, PERSPECTIVES, AND EDITORIALS

Future Concepts in Nanomedicine
Rob Burgess, PhD

Is Translational Medicine the Future of Therapy?
Christopher-Paul Milne, PhD, and James Mittra, PhD

Nanomedical Cognitive Enhancement: Challenges and Future Possibilities
Melanie Swan, MBA

Nanomedicine: Ethical Considerations
Todd Kuiken, PhD

Clinical Nanobioethical Problems: A Value Approach
Jorge Alberto Álvarez-Díaz, MD, PhD

Nanomedicine: Shadow and Substance
Z. Shadi Farhangrazi, PhD, and S. Moein Moghimi, PhD

The Tower of Babel: Miscommunication within and about Nanomedicine
Rudolph L. Juliano, PhD

Is Nanotechnology Toxic? Was Prince Charles Correct?
Pelagie M. Favi, PhD, and Thomas J. Webster, PhD

The Audience Is the Message: Nanomedicine as Apotheosis or Damnatio Memoriae
David M. Berube, PhD

A Sample of Religious Thought on Nanotechnology
Chris Toumey, PhD

Iron Oxide Nanoparticles for Treatment of Anemia of Chronic Kidney Disease: Too Much of a Good Thing?
Amy Barton Pai, PharmD

Perspectives on Legal Challenges in the Development and Commercialization of Nanotechnology
Annette I. Kahler, JD

Nanomedicine and the Fight against H





Autore

Raj Bawa, MS, PhD, is president of Bawa Biotech LLC, a biotech/pharma consultancy and patent law firm based in Ashburn, Virginia that he founded in 2002. He is an inventor, entrepreneur, professor and registered patent agent licensed to practice before the US Patent & Trademark Office. Trained as a biochemist and microbiologist, he has been an active researcher for over two decades. He has extensive expertise in the pharmaceutical sciences, biotechnology, nanomedicine, drug delivery, biodefense, FDA regulatory issues, and patent law. Since 1999, he has held various adjunct faculty positions at Rensselaer Polytechnic Institute in Troy, NY, where he is currently an adjunct professor of biological sciences and where he received his doctoral degree in three years (biophysics/biochemistry). Since 2004, he has been an adjunct professor of natural and applied sciences at NVCC in Annandale, VA. He is a scientific advisor to Teva Pharmaceutical Industries, Ltd., Israel. He has served as a principal investigator of National Cancer Institute SBIRs and reviewer for both the National Institutes of Health and the National Science Foundation. In the 1990s, Dr. Bawa held various positions at the US Patent & Trademark Office, including primary examiner for 6 years. He is a life member of Sigma Xi, co-chair of the Nanotech Committee of the American Bar Association and serves on the Global Advisory Council of the World Future Society. He has authored over 100 publications, co-edited four texts and serves on the editorial boards of numerous peer-reviewed journals, including serving as a special associate editor of Nanomedicine (Elsevier) and an editor-in-chief of the Journal of Interdisciplinary Nanomedicine (Wiley). Some of Dr. Bawa’s awards include the Innovations Prize from the Institution of Mechanical Engineers, London, UK (2008), the Key Award from Rensselaer’s Office of Alumni Relations (2005) and the Lifetime Achievement Award from the American Society for Nanomedicine (2014).

Gerald F. Audette, PhD, has been a faculty member at York University in Toronto, Canada, since 2006. Currently, he is an associate professor in the Department of Chemistry and acting director of the Centre for Research on Biomolecular Interactions at York University. He received his doctorate in 2002 from the Department of Biochemistry at the University of Saskatchewan in Saskatoon, Canada. Working with Drs. Louis T. J. Delbaere and J. Wilson Quail (1995–2001), Dr. Audette’s research focused on the elucidation of the protein– carbohydrate interactions that occur during blood-group recognition (in particular during the recognition of O blood type) using high-resolution X-ray crystallography. Dr. Audette conducted his postdoctoral research at the University of Alberta (2001–2006) in Edmonton, Canada. Working with Drs. Bart Hazes and Laura Frost; his research again utilized high-resolution protein crystallography to examine the correlation between protein structure and biological activity of type IV pilins that are assembled into pili used by bacteria for multiple purposes, including cellular adhesion during infection. It was during these studies that Dr. Audette identified the generation of protein nanotubes from engineered pilin monomers. Dr. Audette also studied the process of bacterial conjugation (or lateral gene transfer) using the F-plasmid conjugative system of Escherichia coli. Current research directions include: structure/function studies of proteins involved in bacterial conjugation systems, the structural and functional characterization of several type IV pilins (the monomeric subunit of the pilus), their assembly systems, and adapting these unique protein systems for applications in bionanotechnology. Dr. Audette has previously served as co-editor- in-chief of the Journal of Bionanoscience (2007–2010), and is currently a subject editor of structural chemistry and crystallography for the journal FACETS.

Brian E. Reese, PhD, JD, MBA, is an associate at the law firm of Choate, Hall, and Stewart in Boston, Massachusetts since 2012. Dr. Reese has extensive experience in intellectual property law, particularly patenting and trademark issues in the life sciences, and brings a practical knowledge of business strategy to his practice. As a former stock analyst, Dr. Reese has a strong appreciation for the business realities his clients face and how intellectual property can help them achieve their objectives. Dr. Reese graduated with a BS in cellular biochemistry from the State University of New York at Plattsburgh, where he received the Chancellor’s Award for academic excellence. He subsequently obtained his PhD from Pennsylvania State University for his research in the areas of neuroscience, molecular biology and toxicology. He also completed his MBA at Pennsylvania State University. Dr. Reese attended Albany Law School in Albany, NY, where he graduated magna cum laude. As a trained neuroscientist, Dr. Reese has authored several scientific and legal research papers in peer- reviewed journals. Each year, he moderates the American Bar Association’s panel on science and technology law at the Current Issues in Medicine and Pharma conference held at Rensselaer Polytechnic Institute in Troy, NY. Dr. Reese is active in providing pro bono services in intellectual property for several entities in the Boston area and currently serves as co-chair of the Nanotech Committee of the American Bar Association.











Altre Informazioni

ISBN:

9789814669221

Condizione: Nuovo
Collana: Pan Stanford Series on Nanomedicine
Dimensioni: 9 x 6 in Ø 4.15 lb
Formato: Copertina rigida
Illustration Notes:36 b/w images and 85 color images
Pagine Arabe: 1502


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