Gastrointestinal Cancers: An Interdisciplinary Approach

Gastrointestinal cancers are among the most prevalent malignancies worldwide, with high rate of global cancer incidence and cancer-related death. Gastrointestinal cancers include esophageal cancer, gastric cancer, colorectal cancer, pancreatic cancer, and liver cancer, which all, except the last one, are covered in this volume.

The fourth volume of the “Interdisciplinary Cancer Research” series, entitled “Gastrointestinal Cancers: An Interdisciplinary Approach” publishes comprehensive volumes on mechanisms of gastrointestinal cancers and novel immunotherapy opportunities and presents the most updated and peer-reviewed chapters on gastrointestinal cancers therapy. This interdisciplinary series is of special value to researchers working on cell biology, immunology, biochemistry, genetics, and practitioners working on oncology and gastroenterology. This is the main concept of Cancer Immunology Project (CIP), which is a part of Universal Scientific Education and Research Network (USERN). This interdisciplinary book will be of special value for researchers, oncologists, and gastroenterologists who wish to extend their knowledge on gastrointestinal cancers. 

Chapter 1. Interdisciplinary Approach in Gastrointestinal Cancers

Chapter 2. Gastrointestinal Cancers: What Is the Real Board of Microenvironment and the Role of Microbiota-Immunity Axis

Chapter 3. Epithelial-Mesenchymal Transition in Gastrointestinal Cancer: From a Basic to a Clinical Approach

Chapter 4. Metabolomics of Gastrointestinal Cancers

Chapter 5. Deregulation of Immune System in Gastric Cancer Development, How Immune Nutrition Might Restore the Functions of Immune Cells

Chapter 6. Helicobacter pylori Virulence Factors, Pathogenicity, and Gastric Cancer

Chapter 7. Gastric Cancer and Helicobacter pylori

Chapter 8. Role of Neuromodulators in Regulation of the Tumor Microenvironment of Gastric and Colorectal Cancers

Chapter 9. The Role of Tumor Microenvironment in Colon Cancer

Chapter 10. Unraveling the Esophageal Cancer Tumor Microenvironment: Insights and Novel Immunotherapeutic Strategies

Chapter 11. The Interplay Between Immunity and Gut Microbiota in Colon Cancer

Chapter 12. Immunotherapy in Gastrointestinal Cancer Focusing on CAR-T Cell Therapy

Chapter 13. Development of Biocompatible Nanocarriers for the Treatment of Colorectal Cancer

Chapter 14. Challenges of Onco-therapeutics in Early Onset Colorectal Cancer

Chapter 15. Unintentional Weight Loss and Malnutrition After Esophageal Cancer and Treatment

Chapter 16. Current Clinical Landscape of Immunotherapeutic Approaches in Pancreatic Cancer Treatment

Chapter 17. The Tumor Microenvironment in Pancreatic Cancer and Challenges to Immunotherapy

Professor Nima Rezaei gained his medical degree (MD) from Tehran University of Medical Sciences and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also spent a short-term fellowship of Pediatric Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital.  Professor Rezaei is now the Full Professor of Immunology and Vice Dean of Research and Technologies, School of Medicine, Tehran University of Medical Sciences, and the co-founder and Head of the Research Center for Immunodeficiencies. He is also the Founder of Universal Scientific Education and Research Network (USERN). Prof. Rezaei has already been the Director of more than 100 research projects and has designed and participated in several international collaborative projects. Prof. Rezaei is the editor, editorial assistant, or editorial board member of more than 40 international journals. He has edited more than 50 international books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 1,200 scientific papers in the international journals.