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Fas Signaling




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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

Springer US

Pubblicazione: 11/2010
Edizione: 1





Trama

Fas Signaling is focused on the signaling mechanisms and biology of the prototypic death receptor Fas, also called CD95 or APO-1. The chapters of this book cover, besides the well recognized apoptosis-related functions of Fas, its emerging role as a proinflammatory cytokine and as an inducer of alternative forms of cell death. Fas Signaling aims to provide the reader with an up-to-date survey of the various aspects of Fas biology and the open questions of the field are addressed. This title is intended for Ph.D and post-doctoral students starting to work in the field, but is also useful for everyone with an interest in the biology of this exciting molecule.





Sommario

FasL and Fas.- FasL-Independent Activation of Fas.- Role of Ceramide in CD95 Signaling.- Regulation of Fas Signaling by FLIP Proteins.- Fas-Induced Necrosis.- Fas—More Than an Apoptosis Inducer.- Retrograde Fas Ligand Signaling.- FasL and Fas in Liver Homeostasis and Hepatic Injuries.- Fas-Activation, Development and Homeostasis of T Cells.- The FasL-Fas System in Disease and Therapy.- Tools for Activation and Neutralization of Fas Signaling.










Altre Informazioni

ISBN:

9781441940742

Condizione: Nuovo
Collana: Medical Intelligence Unit
Dimensioni: 248 x 165 mm
Formato: Brossura
Illustration Notes:VIII, 160 p. 32 illus., 4 illus. in color.
Pagine Arabe: 160
Pagine Romane: viii


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