Enzyme Cascade Design and Modelling

This book provides a comprehensive overview of the recent developments achieved in the field of chemo/enzymatic cascades with topics spanning from design (in vitro and in vivo) to kinetic- and process modelling as well as process control. Opportunities and challenges of building multi-step chemo/enzymatic reactions are discussed, whereby the latter are critically assessed in each chapter and methods to ease the implementation are explored. Both, multi-enzymatic cascades and chemo-enzymatic cascades are presented with the motivation of combining the strengths of these two worlds (e.g. selectivity, activity and robustness) not neglecting the obstacles and challenges of such endeavour. Furthermore, the use of non-conventional media for catalytic cascade reactions, recent achievements and potential for future developments in a technical environment are addressed.   

Prof. Dr. Selin Kara, Department of Biological and Chemical Engineering, Aarhus University, Aarhus, Denmark

Assoc. Prof. Dr. Florian Rudroff, Institute of Applied Synthetic Chemistry, Vienna University of Technology, Vienna, Austria