Chapter 1
1 Introduction
1.1 INTRODUCTORY OVERVIEW
1.2 HISTORY OF ELECTROPHYSIOLOGY
Chapter 2
2 Basics: Theory
2.1 ELECTRICAL CHARACTERISTICS OF BIOLOGICAL MEMBRANES
2.2 ION DISTRIBUTION AT BIOLOGICAL MEMBRANES
2.3 DONNAN DISTRIBUTION AND NERNST EQUATION
2.4 GOLDMAN-HODGKIN-KATZ EQUATION
Chapter 3
3. Basics: Methods
3.1 RECORDING ELECTRICAL SIGNALS FROM BODY SURFACE
3.2 THE EXAMPLE (ECG)
3.3 RECORDING ELECTRICAL SIGNALS FROM TISSUE
3.4 RECORDING ELECTRICAL SIGNALS FROM SINGLE CELLS
3.5 APPLICATION OF THE VOLTAGE-CLAMP TECHNIQUE
3.6 THE PATCH-CLAMP TECHNIQUE
Chapter 4
4 Automated Electrophysiology
4.1 AUTOMATED TWO-ELECTRODE VOLTAGE CLAMP
4.2 AUTOMATED PATCH CLAMP
Chapter 5
5 Ion-selective Channels
5.1 GENERAL CHARACTERISTICS OF ION CHANNELS
5.2 SPECIFIC ION CHANNELS
Chapter 6
6 Theory of Excitability
6.1 THE HODGKIN-HUXLEY DESCRIPTION OF EXCITATION
6.2 CONTINUOUS AND SALTATORY CONDUCTION OF ACTION POTENTIALS
6.3 GENERATION AND TRANSMISSION OF ACTION POTENTIALS
6.4 SUMMARY OF THE DIFFERENT TYPES OF POTENTIALS
6.5 ACTION POTENTIAL IN NON-NERVE CELLS
Chapter 7
7 Carrier-mediated Transport
7.1 GENERAL CHARACTERISTICS OF CARRIERS
7.2 CARRIERS ARE LIKE CHANNELS WITH ALTERNATING GATES
Chapter 8
8 Examples of Application of Electrophysiology
8.1 STRUCTURE-FUNCTION RELATIONSHIPS OF CARRIER PROTEINS
8.2 STRUCTURE-FUNCTION RELATIONSHIPS OF ION CHANNELS
8.3 VIRAL ION CHANNELS
Appendix
A1. THE GRAPH THEORY
A2. INFLUENCE OF EXTERNAL ELECTRICAL AND MAGNETIC FIELDS
A2.1. MAGNETOSTATIC FIELDS
A3. A LABORATORY COURSE:
Important Physical Units
List of Symbols and Abbreviations
Index
