Children with Differences in Sex Development Taking a Multidisciplinary Management Approach

This manual covers all possible aspects of managing a child with differences in sex development, an entity easily missed by the unsuspecting clinician. Managing such children is challenging due to various processes (genetic, hormonal, environmental, chromosomal, and environmental) involved in developing gonads and brain imprinting. The entity of Gender dysphoria adds further to this complexity. With a global uproar caused by the cropping up of medicolegal issues concerning sex allotment and sex of rearing, a need is felt to know about the line of approach to address the problems of management of these children, which does not stop at medical and surgical treatment. Whereas many social and legal organizations are relentlessly working for the cause of such children, there is a lack of comprehensive literature on the round management of such children, which makes the book more of an essential addition to the existing reading material. Esteemed writers give all these aspects and explain lucidly with the help of tables, figures, and diagrams.

Anatomical differentiation and development of gonads.- Molecular regulation  of sexual differentiation.- Hormonal regulation during gonadal development.- rain imprinting during gonadal differentiation.- Gender identity and role.- Gender dysphoria in DSD children.- Metaanalysis and current literature on gender identity  disorders.- Psychopathological and psychiatric co-morbidities ingender dysphoria.-  Legal aspects of DSD Indian & International scenario.- E volution and history of landmark judgements for DSD.- Terminology and clinical evaluation in the Diagnosis of DSD.- Cytogenetic and Molecular Genetic investigations in DSD.- Imaging and Endoscopy in  the Diagnosis of DSD.- Endocrine profiling in diagnosis.- Pathology of DSD.

Dr. Simmi K Ratan (MCh. Pediatric Surgery, DNB Pediatric Surgery) Graduated from Delhi University from Maulana Azad Medical College. She is currently working in the capacity of Director professor at MAMC and has more than 26 years of teaching experience. She has authored more than 150 papers and has delivered numerous oral and poster presentations at national and international meetings. She received the Puru Upadhyay Research Award from the Indian Association of Pediatric Surgeons in 2009. Her biography appears in Marques who’s who series and received Rashtriya Gaurav Award in 2005. She is president of the Pan India Society for Children with Disorders of sexual development.