Biomedical EPR - Part B: Methodology, Instrumentation, and Dynamics

Biomedical EPR – Part B focuses on applications of EPR techniques and instrumentation, with applications to dynamics. The book celebrates the 70^th birthday of Prof. James S. Hyde, Medical College of Wisconsin, and his contributions to this field. Chapters are written to provide introductory material for new-comers to the field that lead into up-to-date reviews that provide perspective on the wide range of questions that can be addressed by EPR.

Key Features:
EPR Techniques including Saturation Recovery, ENDOR, ELDOR, and Saturation Transfer

Instrumentation Innovations including Loop Gap Resonators, Rapid Mixing, and Time Locked Sub-Sampling

Motion in Biological Membranes

Applications to Structure Determination in Proteins

Discussion of Trends in EPR Technology and Prognosis for the Future

Instrumentation and Methodology.- Saturation Recovery EPR.- Loop-Gap Resonators.- EPR Interfaced To Rapid Mixing.- Application of Angle-Selected Electron Nuclear Double Resonance to Characterize Structured Solvent in Small Molecules and Macromolecules.- Solution-ENDOR of Some Biologically Interesting Radical Ions.- Electron-Electron Double Resonance.- Digital Detection by Time-Locked Sampling in EPR.- Measurement of Distances Between Electron Spins Using Pulsed EPR.- Motion, Proteins, and Membranes.- ESR and Molecular Dynamics.- SDSL: A Survey of Biological Applications.- Saturation Transfer Spectroscopy of Biological Membranes.- Saturation Transfer EPR.- Trends in EPR Technology.- Prognosis.

Prof. Sandra S. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. Her research interests include distance measurements in proteins, EPR of metal ions in biological systems, electron spin relaxation times, and EPR instrumentation. The Eatons co-organize an annual EPR Symposium in Denver.

Prof. Gareth R. Eaton is John Evans Professor in the Department of Chemistry and Biochemistry at the University of Denver. His research interests include EPR instrumentation, distance measurements in proteins, EPR of metal ions in biological systems, and electron spin relaxation times.

Dr. Lawrence J. Berliner is currently Professor and Chair of the Department of Chemistry and Biochemistry at the University of Denver after retiring from Ohio State University, where he spent a 32-year career in the area of biological magnetic resonance (EPR and NMR). He is the Series Editor for Biological Magnetic Resonance, which he launched in 1979.