Biomedical Engineering

Several developed countries are facing serious problems in medical environments owing to the aging society, and extension of healthy lifetime has become a big challenge. Biomedical engineering, in addition to life sciences and medicine, can help tackle these problems. Innovative technologies concerning minimally invasive treatment, prognosis and early diagnosis, point-of-care testing, regenerative medicine, and personalized medicine need to be developed to realize a healthy aging society. This book presents cutting-edge research in biomedical engineering from materials, devices, imaging, and information perspectives. The contributors are senior members of the Research Center for Biomedical Engineering, supported by the Ministry of Education, Culture, Sports, Science and Technology, Japan. All chapters are results of collaborative research in engineering and life sciences and cover nanotechnology, materials, optical sensing technology, imaging technology, image processing technology, and biomechanics, all of which are important areas in biomedical engineering. The book will be a useful resource for researchers, students, and readers who are interested in biomedical engineering.

1. Biosensors Using Metal Oxides as a Sensing Material Miyuki Tabata and Yuji Miyahara 2. Biosensors Based on FETs Containing Nanostructures Anri Nakajima 3. Noble Metallic Pt Coating on Silk Textile by a Supercritical CO2-Promoted Metallization Technique towards Applications of Biocompatible Medical Wearable Devices Wan-Ting Chiu, Tso-Fu Mark Chang, Hiromichi Kurosu, and Masato Sone 4. Biosensors Based on Silicon Photonics Shin Yokoyama, Yoshiteru Amemiya, Takeshi Ikeda, Akio Kuroda, and Mitsuhiko Ogihara 5. Reusable Surface Acoustic Wave Immunosensor for Enhanced Monitoring of Airborne House Dust Mite Allergens Koji Toma, Takahiro Arakawa, and Kohji Mitsubayashi 6. Development of Novel Fluorescent Sensors Based on Fluorescent Natural Compounds Tomoya Hirano, Hidetomo Yokoo, Ayumi Ohsaki, and Hiroyuki Kagechika 7. Living-Cell Analysis by Surface Plasmon Resonance and Its Medical Application Yuhki Yanase and Michihiro Hide 8. Oximetry for Various Tissues Using Near-Infrared Spectroscopy Masatsugu Niwayama 9. Development of THz Laser Spectrometer and Its Application for Pharmaceutical Inspection Tetsuo Sasaki, Tomoaki, Sakamoto, and Makoto Otsuka 10. Microwave Imaging for Breast Cancer Screening Takamaro Kikkawa, Hang Song, Koji Arihiro, and Shinsuke Sasada 11. Ultrasonic Transducers and Non-Contact Measurement Technique for Medical and Agricultural Application/Flexible Acoustic Force Sensor Marie Tabaru and Kazuaki Nishimura 12. Time-Resolved CMOS Image Sensors for Biomedical Applications Shoji Kawahito, Yuya Shirakawa, Keiichiro Kagawa, Keita Yasutomi, and De Xing Lioe 13. High-Resolution Optical Microscopy for Bio-Imaging Wataru Inami and Yoshimasa Kawata 14. X-Ray Semiconductor Imaging Device Technology and Medical-Imaging Application Toru Aoki, Katsuyuki Takagi, Hiroki Kase, and Akifumi Koike 15. Deep Learning in Medical Image Processing and Computer-Aided Diagnosis Kenji Suzuki 16. A Hierarchical Type Segmentation Hardware for Colorectal Endoscopic Images with Narrow-Band Imaging Magnification Tetsushi Koide, Toru Tamaki, Shigeto Yoshida, and Shinji Tanaka 17. Robotics in Minimally Invasive Surgery Kenji Kawashima and Takahiro Kanno 18. Ventricular Assist Devices Utilizing Magnetic Bearing Systems Tadahiko Shinshi

Akihiro Miyauchi received his PhD from Tokyo Institute of Technology, Japan, in 1995. He worked for Hitachi Ltd. from 1986 to 2017 and was a visiting scientist at Massachusetts Institute of Technology, USA, from 1995 to 1996. He has been working in semiconductor process, nanoimprint, and biomimetics. The related books were published by Jenny Stanford Publishing. Since 2018, he is a professor at the Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University, Japan. Yuji Miyahara received his PhD from Tokyo Institute of Technology in 1985. He worked for Hitachi Ltd. from 1985 to 2002 and National Institute for Materials Science, Japan, from 2002 to 2010. Since 2010, he is a professor at the Institute of Biomaterials and Bioengineering, Tokyo Medical and Dental University. He has been working in the field between electronics and biotechnology for more than 35 years. Based on the semiconductor technology, he has developed several types of biosensors and sensing technologies for life science and medical fields.