The Biological Basis of Cancer 2ND EDITION

This book, designed to be used for an undergraduate course on cancer biology, is aimed at upper division undergraduates with a background in freshman biology, as well as beginning graduate students. An introduction acquaints students with the biological principles of cancer, and the human dimensions of the disease by considering genuine cases of cancer. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer and a glossary.

This is a revised and updated edition of a text used in undergraduate courses on cancer biology. It covers everything from the molecular basis of cancer to clinical aspects of the subject, and has a lengthy bibliography designed to assist newcomers with the cancer literature. An introduction acquaints students with the biological principles of cancer and the human dimensions of the disease by considering genuine cases of cancer in fictionalized letters. Other chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Also included are an appendix with descriptions of common forms of cancer, a glossary of cancer-related terms and colour plates to illustrate the pathology of many of the types of cancer discussed in the text. Upper-division undergraduates with a background in freshman biology and chemistry, as well as beginning graduate students will find this a valuable text.

Preface; Introduction: letters illustrating clinical aspects of cancer G. Barry Pierce; 1. The pathology of cancer G. Barry Pierce; 2. Metastasis Robert G. McKinnell; 3. Carcinogenesis Alan O. Perantoni; 4. Cancer genetics Robert G. McKinnell; 5. Oncogenes and suppressors; Alan O. Perantoni; 6. Cancer in organisms other than humans Robert G. McKinnell; 7. Epidemiology Robert G. McKinnell; 8. Cancer treatment Ralph E. Parchment; 9. Biological therapy Ralph E. Parchment; Appendices: A. Description of selected tumors G. Barry Pierce; B. Glossary Robert G. McKinnell; References; Index.

This text, designed for undergraduates taking a cancer biology course, covers everything from the molecular to clinical aspects of the subject. Chapters discuss cancer pathology, metastasis, carcinogenesis, genetics, oncogenes and tumor suppressors, epidemiology, and the biological basis of cancer treatment. Included are an appendix describing selected cancers, and a glossary.