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huang jingshan (curatore); borchert glen m. (curatore); dou dejing (curatore); huan jun (luke) (curatore); lan wenjun (curatore); tan ming (curatore); wu bin (curatore) - bioinformatics in microrna research

Bioinformatics in MicroRNA Research

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Lingua: Inglese


Pubblicazione: 08/2018
Edizione: Softcover reprint of the original 1st ed. 2017


This thorough volume provides an in-depth introduction to and discussion of microRNAs (miRs) and their targets, miR functions, and computational techniques applied in miR research, thus serving the need for a comprehensive book focusing on miR target genes, miR regulation mechanisms, miR functions performed in various human diseases, and miR databases/knowledgebases. Without prior knowledge of the area of study, computational biologists, computer scientists, bioinformaticians, bench biologists, as well as clinical investigators will find it easy to follow the techniques in this collection. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of detailed implementation advice that ensures successful results. 

Accessible and practical, Bioinformatics in MicroRNA Research functions as an ideal guide for researchers of all backgrounds to explore this vital area of study.


1. MicroRNAs, Long Non-Coding RNAs, and Their Functions in Human Disease

            Min Xue, Ying Zhuo, and Bin Shan


2. MicroRNA Expression: Protein Participants in MicroRNA Regulation

            Valeria M. King and Glen M. Borchert


3. Viral MicroRNAs, Host MicroRNAs Regulating Viruses, and Bacterial MicroRNA-Like RNAs

            Sara-Elizabeth Cardin and Glen M. Borchert


4. MicroRNAs: Biomarkers, Diagnostics, and Therapeutics

            Weili Huang


5. Relational Databases and Biomedical Big Data

            N.H. Nisansa D. de Silva


6. Semantic Technologies and Bio-Ontologies

            Fernando Gutierrez


7. Genome-Wide Analysis of MicroRNA-Regulated Transcripts

            David Chevalier and Glen M. Borchert


8. Computational Prediction of MicroRNA Target Genes, Target Prediction Databases, and Web Resources

            Justin T. Roberts and Glen M. Borchert


9. Exploring MicroRNA::Target Regulatory Interactions by Computing Technologies

            Yue Hu, Wenjun Lan, and Daniel Miller


10. The Limitations of Existing Approaches in Improving MicroRNA Target Prediction Accuracy

            Rasiah Loganantharaj and Thomas A. Randall


11. Genomic Regulation of MicroRNA Expression in Disease Development

            Feng Liu


12. Next Generation Sequencing for MicroRNA Expression Profile

            Yue Hu, Wenjun Lan, and Daniel Miller


13. Handling High-Dimension (High-Feature) MicroRNA Data

            Yue Hu, Wenjun Lan, and Daniel Miller


14. Effective Removal of Noisy Data Via Batch Effect Processing

            Ryan G. Benton


15. Logical Reasoning (Inferencing) on MicroRNA Data

            Jingsong Wang


16. Machine Learning Techniques in Exploring MicroRNA Gene Discovery, Targets, and Functions

            Sumi Singh, Ryan G. Benton, Anurag Singh, and Anshuman Singh


17. Involvement of MicroRNAs in Diabetes and Its Complications

            Bin Wu and Daniel Miller


18. MicroRNA Regulatory Networks as Biomarkers in Obesity: The Emerging Role

            Lihua Zhang, Daniel Miller, Qiuping Yang, and Bin Wu


19. Expression of MicroRNAs in Thyroid Carcinoma

            Gaohong Zhu, Lijun Xie, and Daniel Miller

Altre Informazioni



Condizione: Nuovo
Collana: Methods in Molecular Biology
Dimensioni: 254 x 178 mm Ø 566 gr
Formato: Brossura
Illustration Notes:X, 285 p. 24 illus., 18 illus. in color.
Pagine Arabe: 285
Pagine Romane: x

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