Aromatherapy Basic Mechanisms and Evidence Based Clinical Use

Recent clinical studies have demonstrated an impact of aromatherapy on the control of symptoms associated with human diseases not fully controlled by conventional therapy. Aromatherapy: Basic Mechanisms and Evidence Based Clinical Use provides an up-to-date compilation of background scientific information that advocates the application of currently developed clinical studies on the effects of aromatherapy to the treatment of human diseases such as mild, stress-induced mood disorders, infectious diseases, and age-related disturbances. The book encompasses all aspects of successful clinical use of aromatherapy, including phytochemistry, technology, and clinical trials. It outlines a rational basis for clinical translation of aromatherapy for treating human diseases in need of safer therapies. It also describes evidence-based use of aromatherapy in controlling clinical manifestations of severe diseases for which conventional therapies often fail, such as managing agitation and aggression associated with Alzheimer’s disease and other neurodegenerative diseases. Containing a wealth of references and a thorough presentation of knowledge on essential oils and aromatherapy, this book is a valuable resource for students, researchers, clinicians, and policy makers in health care systems. It details the current clinical uses of aromatherapy while promoting further clinical development in areas where therapy is lacking.

Historical Notes on Essential Oils and Aromatherapy with Special Reference to Bergamot Essential OilAlfredo Focà and Maria Carla LibertoThe Olfactory System: From Odorant Molecules to PerceptionSimone Pifferi and Anna MeniniBOTANICAL, PHYTOCHEMICAL, ANALYTICAL, AND TECHNOLOGICAL ISSUESTaxonomy, Morphology, and Physiology of Aromatic Plants: A Botanical PerspectiveSalvatore RagusaPhytochemical Components of Aromatic Plants and Factors Influencing Their VariabilityGiancarlo StattiAromatic Plants: Molecular Biology/Biotechnology ApproachCandida Vannini and Marcella BracaleExtraction, Sample Preparation, and Analytical Methods for Quality Issues of Essential OilsPaola Montoro, Milena Masullo, Sonia Piacente, and Cosimo PizzaTechnological Aspects of Essential OilsMaria Chiara Cristiano, Donato Cosco, and Donatella PaolinoCELL BIOLOGICAL EFFECTS AND UNDERLYING MECHANISMSEssential Oils Exploited in Cytotoxicity Studies for Translation into Safer and More Effective Cancer TherapeuticsRossella Russo, Maria Tiziana Corasaniti, Giacinto Bagetta, and Luigi Antonio MorronePhototoxicity of Essential OilsMichele Navarra, Marco Miroddi, and Gioacchino CalapaiEssential Oils: Fragrances and AntioxidantsRosalia Crupi and Salvatore CuzzocreaRATIONAL BASIS FOR AROMATHERAPYAromatherapy and Neurotransmission: Behavioral and Neurochemical StudiesLuigi Antonio Morrone, Laura Rombolà, Diana Amantea, Maria Tiziana Corasaniti, and Giacinto BagettaRational Basis for Research and Development of Essential Oils in Pain TrialsLaura Rombolà, Luigi Antonio Morrone, Chizuko Watanabe, Hirokazu Mizoguchi, Tsukasa Sakurada, Laura Berliocchi, Maria Tiziana Corasaniti, Giacinto Bagetta, and Shinobu SakuradaPain Relief by Local Peripheral Injection of Beta-Caryophyllene through Cannabinoid 2 ReceptorSoh Katsuyama, Takaaki Komatsu, Giacinto Bagetta, Shinobu Sakurada, and Tsukasa SakuradaEssential Oils, the Immune System, and InflammationFranca Marino, Raffaella Bombelli, and Marco CosentinoAntimicrobial Effects of Bergamot Essential Oil: From Ancient Medicine to Modern ResearchAlfredo Focà and Maria Carla LibertoEVIDENCE BASED CLINICAL USE OF AROMATHERAPYAromatherapy for the Treatment of Neuropsychiatric Symptoms of DementiaLuca Cravello and Carlo CaltagironeAromatherapy in Dementia and Dementia-Related Neuropsychiatric DisordersSergio Fusco, Francesco Corica, and Andrea CorsonelloTherapeutic Applications of Aromatherapy in PediatricsSamaneh Khanpour Ardestani, Cecilia Bukutu, and Sunita VohraAromatic Plants and Essential Oils in the Treatment and Prevention of Infectious DiseasesNeda Mimica-Dukic, Natasa Simin, Ivana Beara, Dejan Orcic, Marija Lesjak, Marina Franciškovic, and Emilija SvircevREGULATORY ISSUESRegulatory Issues in AromatherapyGioacchino CalapaiPharmacovigilance and Phytovigilance for a Safe Use of Essential OilsAlfredo Vannacci, Alessandra Pugi, Eugenia Gallo, Fabio Firenzuoli, and Alessandro MugelliEssential Oils and Aromatherapy: Epidemiology of Their UtilizationAnna Loraschi and Marco Cosentino

Giacinto Bagetta, University of Calabria, Rende, Italy Marco Cosentino, University of Insubria, Varese, Italy Tsukasa Sakurada, Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan