Contributing Authors. A:- Principles of Angiogenesis in the Central Nervous System. 1. Vasculogenesis and Angiogenesis; S. Patan. 2. Morphogenesis of Embryonic CNS Vessels; H. Kurz, J. Korn, B. Christ. 3. Mathematical Modeling of Tumour-Induced Angiogenesis: Network Growth and Structure; M. Chaplain, A. Anderson. B:- Assessment of Angiogenesis in Neuro-Oncology. 4. Histologic Measures of Angiogenesis in Human Primary Brain Tumors; R.D. Folkerth. 5. Angiogenesis in Transgenic Models of Multistep Angiogenesis; I. Radovanovic, M.G. D'Angelo, A. Aguzzi. 6. Models for Angiogenesis in Gliomas; R.H. Goldbrunner, M. Bendszus, J.-C. Tonn. 7. Protocol for Isolation of HCEC; R.H. Goldbrunner, M. Bendszus, J.-C. Tonn. 8. Protocol for MRI Monitoring of Orthotopic Glioma Growth in the Rat Brain; R.H. Goldbrunner, M. Bendszus, J.-C. Tonn. 9. Methods to Study Angiogenesis in vitro; K. Lamszus, O. Heese, M. Westphal. 10. The Rabbit Corneal Pocket Assay for the Study of Angiogenesis; L. Morbidelli, M. Ziche. C:- Brain Tumor Related Angiogenesis. 11. Role of Nitric Oxide in Tumor Angiogenesis; L. Morbidelli, S. Donnini, M. Ziche. 12. Angiogenesis-related Growth Factors in Brain Tumors; K. Lamszus, O. Heese, M. Westphal. 13. Role of VEGF in Developmental Angiogenesis and in Tumor Angiogenesis in the Brain; M.R. Machein, K.H. Plate. 14. Hypoxia and Hypoxia Inducible Factors (HIF) as Important Regulators of Tumor Physiology; T. Acker, K.H. Plate. 15. Vascular Microenvironment in Gliomas; P. Vajkoczy, M.D. Menger. 16. Angiogenesis and Invasion in Gliomas; L. Bello, C. Giussani, G. Carrabba, M. Pluderi, F. Costa, A. Bikfalvi. 17. Metastasis and Angiogenesis; M. Kirsch, G. Schackert, P.McL. Black. D:- Clinical Application in Neuro-Oncology. 18. Inhibition of Angiogenesis as a Therapeutic Strategy Against Brain Tumors; V.K. Puduvalli. 19. Anti-Angiogenic Chemotherapy in Central Nervous System Tumors; M.W. Kieran. Index.