Advances in Non-coding RNAs in Cancer-Biology and Immunology covers the machinery of non-coding RNAs, including microRNA, LnRNA and piRNA, the identification of targets of these non-coding RNAs, and the identification of physiological and pathological roles of miRNAs, LnRNAs and piRNAs in immunology and cancer biology. The book introduces basic ideas of miRNAs, LnRNAs and piRNAs, along with detailed bio-processing steps, critical functions in the development of tumorigenesis and controlling immune cell responses, benefits for identifying different classes of non-coding RNAs and their targets, and finally, tactics on how to identify new members of these non-coding RNAs and predict possible functions.
In addition, the book captures the essence of the pioneering work of some of the world's leading researchers, showcasing the scientific excitements surrounding the evolving regulatory roles of miRNAs, LnRNAs and piRNAs, while also highlighting their potential towards the diagnosis and therapeutics of various diseases.
- Provides a unified, cutting-edge resource for non-coding RNAs, including miRNAs LnRNAs, and piRNAs and their physiological and pathological roles and potential applications
- Showcases high-throughput technologies and other approaches for the discovery of these non-coding RNAs and their downstream targets
- Unveils the diverse molecular mechanisms by which miRNAs, LnRNAs and piRNAs regulate gene expression in animal cells
- Showcases recent discoveries on the involvement of these non-coding RNAs in different biological processes and diseases as well as their possible use in diagnosis
- Reports breakthroughs in the use of these non-coding RNAs for diagnosis and personalized therapy
