Adenosine, Cardioprotection and Its Clinical Application

I. Adenosine and Cardioprotection.- 1. Adenosine and Cardioprotection.- II. Cardioprotection and Mechanisms of Ischemic and Reperpusion Injury.- 2. Concept of Cardioprotection Against Myocardial Ischemia.- 3. The Late Phase of Preconditioning Against Myocardial Stunning.- 4. Coronary Perfusion as the Major Determinant of Myocardial Contractility in the Heart: Implication for Myocardial Hibernation.- 5. Myocardial Protection From Reperfusion Injury With Adenosine.- III. Cellular Mechanisms of Cardioprotection in Ischemic Preconditioning.- 6. Protein Kinase C - the Key-Enzyme in Ischémic Preconditioning?.- 7. Adenosine, Cardioprotection and Potential Mechanisms.- 8. Activation of Ecto-5'-nucleotidase Mediates Cardioprotection in Ischemic Preconditioning: Important Role of Protein Kinase C.- 9. Role of Mn-SOD Induction in the Second Window Phenomenon of Preconditioning of Ischemic Hearts.- 10. Opioid Receptors, KATP Channels and Ischemic Preconditioning.- 11. Bradykinin and Preconditioning Against Infarction.- 12. Preconditioning in Human Muscle and Myocytes.- 13. Protein Kinase C and Adenosine Synergistically Activate ATP-Sensitive Potassium Currents: Implications for Ischemic Preconditioning.- Clinical Application of New Strategies to Protect The Ischemic Heart.- 14. Adenosine and Myocardial Protection in Humans.- 15. Clinical Applications of Ischemic Preconditioning.- 16. Clinical Pharmacology of Preconditioning and Adenosinergic Drugs.- 17. Clinical Application of Ischemic Preconditioning by ATP-Sensitive Potassium Channel Openers.- 18. Potassium Channel Openers and Cardiac Surgery.- 19. Anti-ischemic Effects of the ATP-sensitive Potassium Channel Opener During Coronary Angioplasty.- 20. Clinical Impact of Ischemic Preconditioning on Infarct Size and CoronaryNo-reflow Phenomenon after Successful Recanalization in the Acute Myocardial Infarction.