The Macrophage

TRAMA

The field of macrophage research has grown enormously since publication of the first edition of this book. The Macrophage 2e provides a unique comprehensive review of the current scientific knowledge of the multifaceted role of this important and intriguiging cell in health and disease. In 16<BR>chapters by experts in the field it covers the basic biology and diverse functions of macrophages in specific diseases and the complex of interactions between macrophages and other cells. Ranging from their role in the defense against pathogens, their role as hosts for pathogens (including HIV), <BR>their complex roles in diseases such as arthritis and cancer, and their potential for use in novel gene therapy approaches to disease treatment, the book gives an up to the minute account of active macrophage research. The editors have intentionally included a broad rangeof topics that will appeal<BR>not only to immunologists and cell biologists but will also be of interest to those working in the specific disease areas covered.

SOMMARIO

1 - The biology of the macrophage2 - Molecular basis of macrophage activation: from gene expression to phenotypic diversity3 - Macrophages as antigen presenting cells: relationship to dendritic cells and use in vaccination studies4 - Macrophage-virus interactions5 - Macrophages in bacterial infection6 - Macrophages in parasitic infection7 - Macrophages and Alzheimer's Disease8 - Macrophages in autoimmunity and primary immunodeficiency9 - Macrophages in rheumatoid arthritis10 - Macrophages in wound healing11 - Macrophages in tumour biology12 - Macrophages in cardiovascular disease13 - Macrophages in the central nervous system14 - Macrophages in reproductive biology15 - Macrophages in gene therapy: cellular targets and gene delivery vehicles16 - Use of mathematical modelling to simulate and predict macrophage activity in diseased tissues

ALTRE INFORMAZIONI

• Condizione: Nuovo
• ISBN: 9780192631978
• Dimensioni: 248 x 40.6 x 174 mm Ø 1318 gr
• Formato: Copertina rigida
• Illustration Notes: 3pp colour plates, numerous black and white photographs and figures
• Pagine Arabe: 680