Structural Biology Using Electrons and X-rays

NOTE EDITORE

Structural Biology Using Electrons and X-Rays discusses the diffraction and image-based methods used for the determination of complex biological macromolecules. The book focuses on the Fourier transform theory, which is a mathematical function that is computed to transform signals between time and frequency domain. Composed of five parts, the book examines the development of nuclear magnetic resonance (NMR), which allows the calculation of the images of a certain protein. Parts 1 to 4 provide the basic information and the applications of Fourier transforms, as well as the different methods used for image processing using X-ray crystallography and the analysis of electron micrographs. Part 5 focuses entirely on the mathematical aspect of Fourier transforms. In addition, the book examines detailed structural analyses of a specimen's symmetry (i.e., crystals, helices, polyhedral viruses and asymmetrical particles). This book is intended for the biologist or biochemist who is interested in different methods and techniques for calculating the images of proteins using nuclear magnetic resonance (NMR). It is also suitable for readers without a background in physical chemistry or mathematics. Emphasis on common principles underlying all diffraction-based methodsThorough grounding in theory requires understanding of only simple algebraVisual representations and explanations of challenging contentMathematical detail offered in short-course form to parallel the text

SOMMARIO

Part I: Fourier Transforms 1. Overview 2. Correlations & Convolutions 3. Fourier Fundamentals 4. Digital Fourier Transforms 5. Filters 6. Two-Dimensional FTs Part II: Optics 7. Microscopy with Rays 8. Waves 9. Wave Imaging Part III: Further Mathematical Methods/General Aspects 10. Symmetry 11. Statistics & Matrices 12. The Third Dimension Part IV: Image Analysis/Structure Determination 13. Special Symmetries 14. Crystalline Sheets 15. Helices 16. Icosahedral Particles 17. Unsymmetrical ("Single") Particles 18. Distortion Correction 19. FT Mathematics 20. Elementary Matrices

ALTRE INFORMAZIONI

• Condizione: Nuovo
• ISBN: 9780123705815
• Dimensioni: 235 x 191 mm
• Formato: Brossura
• Pagine Arabe: 450