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An up to date look at the role of astrocytes in CNS function and dysfunction, this volume emphasizes the unique capacity of astrocytes for diverse cellular connection and the resulting implications. Beginning with an examination of functional biomarkers at the cellular interface between astrocytes and a wide range of CNS cells, chapters cover molecular components including ion channels, transporters, and membrane receptors; astrocyte types and subtypes; and astrocyte cellular partners such as neurons, oligodendrocytes, and brain endothelial cells. The second section considers the astrocyte action in epilepsy, neuro-inflammation, and psychiatric disorders.
Introduction: Astrocyte, a Polarized Cell. Functional Biomarkers at the Interfaces. Molecular Components at Astrocyte Interface. Astrocyte Types and Subtypes. Astrocyte Cellular Partners: Establishing Functional Units. CNS Pathology and the Disruption of Astrocyte Connectivity. Epilepsy. Neuro-inflammation. Psychiatric Disorders. Major depressive disorder and Schizophrenia.
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