Upper Airway Stimulation in Obstructive Sleep Apnea Best Practices in Evaluation and Surgical Management

This book by leading international experts provides an evidence-based approach to electrical stimulation of the upper airway, beginning with patient selection, implant techniques, trouble shootings, patient pathways, titrations during daytime and sleep as also new innovative techniques such as stimulation of the ansa cervicalis and the phrenic nerve. 

Key Features: 

• ·       Superbly illustrated schematic drawings and full-colored photographs;
• ·       Step-by-step description of surgical concepts and techniques on all of the market available systems (Inspire, Nyxoah, LivaNova, Remede);
• ·       Complete online media library with videos on the surgical procedures;
• ·       New surgical steps presented for well established procedures (e.g. 2-incicions technique);
• ·       Discussion of outcomes, success rates, risks, and potential troubleshooting’s, where evidenced-based data are not available, expert opinion is provided.  

Upper Airway Stimulation in Obstructive Sleep Apnea will be welcomed by residents, fellows, and board-certified surgeons in otorhinolaryngology and head and neck surgery.

1.      The burden of obstructive sleep apnea: A clarion call to act. 

2.      Treatment options in Sleep Apnea. 

3.      Effect of Hypoglossal Nerve Stimulation on Cardiovascular Outcomes.

4.      History of electrical stimulation in sleep apnea. 

5.      Embryology of the Hypoglossal nerve. 

6.      Considerations of Facial Skeletal Morphology to Optimize Upper Airway Stimulation.  

7.      The Hypoglossal nerve and its anatomical variability. 

8.      Patient Selection, including drug induced sleep endoscopy. 

9.      Overview of different HN-Stimulation systems.

10.  Inspire:

11.  Livanova: 

12.  Nyxoah: 

13.  Upper Airway Stimulation Therapy: an evaluation of outcomes. 

14.  Surgical techniques in upper airway stimulation.

15.  Treatment pathway.

16.  Trouble shooting. 

17.  Hypoglossal Nerve Stimulator in Pediatric Down Syndrome Patients. 

18.  Daytime polysomnography in upper airway stimulation. 

19.  Phrenic Nerve Stimulation in central apnea. 

20.  Stabilizing sleep through closed-loop acoustic stimulation; implications for obstructive sleep apnea treatment. 

21.  Special cases. 

22.  Ansa cervicalis stimulation for obstructive sleep apnea.

23.  Future Perspective of electrical stimulation in sleep apnea.

Clemens Heiser, MHBA, PhD

Associate Professor

Department of Otorhinolaryngology, Head and Neck Surgery Somnology

Head of Sleep Laboratory

Klinikum rechts der Isar

Technische Universität München

Munich, Germany

Prof Dr. Nico de Vries

Department of ENT, OLVG West, Amsterdam, The Netherlands

Department of Oral Kinesiology, ACTA, Amsterdam

Department of ENT, University of Antwerp, Belgium

Amsterdam, The Netherlands