The Spectrum of Psychotic Disorders Neurobiology, Etiology and Pathogenesis

The spectrum of psychotic disorders encompasses as many as 25 different etiologies, ranging from the primary psychoses through those secondary to medical conditions, drugs and medications, and sensory impairments. This book provides a one-stop, comprehensive review of these disorders and gives quick comparisons for diagnostic decision-making to help with difficult differential diagnoses. Every chapter is uniformly structured to show comparisons between each disorder of presentation, course, and underlying neuropathology. Evidence for each etiology is also rated, indicating the confidence level the reader can place in the current findings. The international team of authors also examines data supporting a unitary neurobiological model of psychosis and the hypothesis that psychosis is a neurobiological syndrome similar to aphasia or apraxia. This book represents a paradigm shift in understanding, classifying and diagnosing these disorders, providing directions for future research and treatment. It will be of great interest to psychiatrists and neuroscientists alike.

Part I. Introduction: 1. Introduction: is psychosis a neurobiological syndrome? Daryl E. Fujii and Iqbal Ahmed; Part II. Primary Psychotic Disorders: 2. Schizophrenia Gerald Goldstein, Daniel N. Allen and Gretchen L. Haas; 3. Childhood onset schizophrenia Jason Schiffman; 4. Late onset schizophrenia Katerine Osatuke, John W. Kasckow and Somaia Mohamed; 5. Schizoaffective disorder David B. Arciniegas and Daniel J. Abrams; 6. Schizophreniform and brief psychotic disorder Andreas Marneros and Frank Pillman; 7. Delusional disorders Theo Manschrek; Part III. Mood Disorders: 8. Psychosis in bipolar disorder Deborah Yurgelun-Todd; 9. Psychosis in major depression Eric G. Smith, Philip R. Burke, Jessica E. Grogan, Susan E. Frantoni and Anthony J. Rothschild; Part IV. Neurodevelopmental and Genetic Disorders: 10. Psychosis associated with intellectual deficits Nick Bouras and Colin P. Hemmings; 11. Psychosis secondary to velo-cardio-facial syndrome Wendy R. Kates and Wanda Fremont; 12. Psychosis secondary to autism Dirk M. Dhossche; Part V. Central Nervous System Disorders: 13. Psychosis secondary to traumatic brain injury Daryl E. Fujii, Nikki Armstrong and Iqbal Ahmed; 14. Psychosis secondary to epilepsy Perminder Sachdev; 15. Psychosis secondary to cerebral vascular accident James A. Bourgeois; 16. Psychosis secondary to brain tumors Tamara Dolenc and Teresa Rummans; 17. Psychosis secondary to infections Sarah Reading and John T. Little; 18. Psychosis secondary to inflammatory and demyelinating Disease Katherine H. Taber and Robin A. Hurley; Part VI. Substance Abuse and Medications: 19. Psychosis secondary to cannabis abuse Luis Alfonso Nunez Domingo; 20. Psychosis secondary to cocaine abuse Daryl E. Fujii and Erin Y. Sakai; 21. Psychosis secondary to methamphetamine abuse Liz Jacob and William Haning III; 22. Psychosis secondary to medications Junji Takeshita, Diane Thompson and Stephen E. Nicolson; Part VII. Neurodegenerative Disorders: 23. Psychosis secondary to dementia of the Alzheimer's type Robert A. Sweet; 24. Psychosis secondary to Lewy Body Dementia Sasha Ericksen and Debby Tsuang; 25. Psychosis secondary to Parkinson's Disease David L. Sultzer and G. Webster Ross; Part VIII. Sensory Impairments: 26. Psychosis secondary to deafness, blindness, and release hallucinations Suzanne Holroyd; Part IX. Conclusion: 27. Is psychosis and neurobiological syndrome: integration and conclusions Daryl E. Fujii and Iqbal Ahmed.

This 2007 book provides a one-stop, comprehensive review of the spectrum of psychotic disorders, giving quick comparisons for diagnostic decision-making, evidence for each etiology, and examining the data describing a unitary neurobiological model of psychosis along with the hypothesis that psychosis is a neurobiological syndrome similar to aphasia or apraxia.