The average life expectancy has increased worldwide in the recent decades. This has presented new challenges as old age brings the onset of diseases such as cancer, neurodegenerative disorders, cardiovascular disease, type 2 diabetes, arthritis, osteoporosis, stroke, and Alzheimer’s disease. Studies and research have shown the potential preventive and therapeutic roles of antioxidants in aging and age-related diseases by inhibiting the formation or disrupting the propagation of free radicals and thus increasing healthy longevity, enhancing immune function, and decreasing oxidative stress. This has made an antioxidant rich diet of increasing importance in battling the detrimental effects of the aging process.
“The Role of Antioxidants in Longevity and Age-Related Diseases” is the book that compiles research on antioxidants and their biological mechanisms that mediate age-related diseases. This book covers the major issues linked to antioxidants, aging, and age-related diseases, including changes in organ systems over the lifespan, age-related oxidative stress-induced redox imbalance, inflammaging, implications of inflammation in aging and age-related diseases, and the important role of antioxidant-rich foods in their prevention and treatment of various age-related diseases.For researchers seeking a comprehensive single source on antioxidants and their roles in aging and age-related diseases, this novel text provides an up-to-date overview.
1 Introduction and Background
2 Changes in Organ Systems over the Lifespan
3 Age-Related Oxidative Stress-Induced Redox Imbalance
4 Chronic Inflammation and Aging (Inflammaging)
5 Implications of Inflammation in Aging and Age-Related Diseases
5.2 Neurodegenerative Diseases
6 Antioxidant and Age-Related Diseases
7 The Role Antioxidant on Health and Age-Related Diseases in Aging
7.1 Low Molecular Weight Antioxidant
7.5 Dietary Minerals
7.6 Ascorbic Acid
7.7 Vitamin E
7.9 Organosulfur Compounds
7.10 Ergothioneine, Betalains, and Carnosine/Anserine
8 Summary and Future Prospects
Dr. Bee Ling Tan is a researcher in the Department of Nutrition, Faculty of Medicine and Health Sciences at the Universiti Putra Malaysia in Serdang, Selangor, Malaysia.
Dr. Mohd Esa Norhaizan is an Associate Professor in the Department of Nutrition, Faculty of Medicine and Health Sciences at the Universiti Putra Malaysia in Serdang, Selangor, Malaysia.
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