Edizione: Softcover reprint of the original 1st ed. 1987
In this book we attempt a synthesis of knowledge from two investigative extremes. On the one hand, neurophysiology and neuropharmacology are progressing via the single neuron to a subcellular level; on the other, clinicians are studying the function ofthe human urinary system in vivo as a whole. A special effort must be made over the next decade to bridge this gap. We hope that the information summarized here will catalyse the process. In 1968, de Groat and Ryall published a group of papers in the Journal of Physiology in which modern quantitative electrophysiological techniques were applied to the study ofthe reflexes that regulate bladder Junction. These papers represent alandmark in the history of bladder neurophysiology, forming a dividing li ne between old and new. The earlier techniques of lesioning and stimulation of nervous structures yielded mainly qualitative information which was open to criticism because of lack of precise control over what was actually being destroyed or stimulated. Much of this earlier work was reviewed in an authoritative volume by Bors and Comarr in 1971, entitled Neurolqgical Urology. The 16 years have seen great advances in our understanding ofthe control oflower subsequent urinary tract function.
Section 1: Neuromorphology.- and Terminology.- 1. Structure and Innervation in the Human.- 2. Comparative Neuromorphology in Animals.- 3. Neural Connections Between the Lower Urinary Tract and the Spinal Cord.- Section 2: Sensation and Motor Control.- 4. Sensations Arising from the Lower Urinary Tract.- 5. The Functions of Efferent Nerves to the Lower Urinary Tract.- 6. Physiology of Bladder Smooth Muscle.- 7. Reflex Control of the Lower Urinary Tract.- 8. Bladder Control: Role of Higher Levels of the Central Nervous System.- Section 3: Clinical Physiology.- 9. Urodynamics.- 10. Clinical Neurophysiology.- 11. Human Physiology.