The Biology Of Mrna: Structure And Function - Oeffinger Marlene (Curatore); Zenklusen Daniel (Curatore) | Libro Springer 01/2021 -

home libri books ebook dvd e film top ten sconti 0 Carrello

Torna Indietro

oeffinger marlene (curatore); zenklusen daniel (curatore) - the biology of mrna: structure and function

The Biology of mRNA: Structure and Function


Disponibilità: Normalmente disponibile in 15 giorni

124,98 €
118,73 €

Questo prodotto usufruisce delle SPEDIZIONI GRATIS
selezionando l'opzione Corriere Veloce in fase di ordine.

Pagabile anche con 18App Bonus Cultura e Carta del Docente

Facebook Twitter Aggiungi commento

Spese Gratis


Lingua: Inglese


Pubblicazione: 01/2021
Edizione: 1st ed. 2019


The book provides an overview on the different aspects of gene regulation from an mRNA centric viewpoint, including how mRNA is assembled and self-assembles in a complex consisting of RNA and proteins, and how its ability to be translated at the right time and space depends on many processes acting on the mRNAs, leading to a properly folded complex. 
This book shows how new technologies have led to a better understanding of these processes and their connected diseases.
The book is written for scientists in fundamental and applied biomedical research working on different aspects of gene regulation. It is also targeted to an audience that is not implicated in these fields directly, but wants to gain a better understanding of mRNA biology.


Regulation of co-transcriptional mRNP assembly.- mRNA export through the NPC.- Roles of mRNA modifications in gene regulation.- Studying mRNPs using single molecule approaches.- Difference between mRNPs and lncRNAs?.- RNPs and/or sequence motives in mRNA localization.- mRNP structure.- New RNA binding proteins: mRNP composition.- Aggregation of repeats RNAs in neurodegenerative diseases.- mRNA structural organization and translation.- How to decide to make an mRNA  - degradation.- Methods to study mRNP composition.- mRNA-DNA kisses – R-loops.- Forms of mRNA editing and their role in disease.


Marlene Oeffinger is Associate Research Professor at the Institut de recherches cliniques de Montréal (IRCM) and the Department of biochemistry and molecular medicine at the Université de Montréal in Montréal, Canada, and Adjunct Professor in the Division of Experimental Medicine at McGill University. Her laboratory uses Proteomic, RNomic and biochemical approaches to study the regulation, dynamics and functional niches of RNA maturation pathways and their implications in neurodegenerative diseases.

Daniel Zenklusen is an Associate Professor at the Department of biochemistry and molecular medicine at the Université de Montréal in Montréal, Canada. His laboratory uses single molecule and super-resolution microscopy approaches to study different aspects of gene expression in single cells, including RNA transport and localization, lncRNAs function and mRNP organization.

Altre Informazioni



Condizione: Nuovo
Collana: Advances in Experimental Medicine and Biology
Dimensioni: 235 x 155 mm Ø 583 gr
Formato: Brossura
Illustration Notes:1 Illustrations, black and white
Pagine Arabe: 312
Pagine Romane: viii

Utilizziamo i cookie di profilazione, anche di terze parti, per migliorare la navigazione, per fornire servizi e proporti pubblicità in linea con le tue preferenze. Se vuoi saperne di più o negare il consenso a tutti o ad alcuni cookie clicca qui. Chiudendo questo banner o proseguendo nella navigazione acconsenti all’uso dei cookie.