Questo prodotto usufruisce delle SPEDIZIONI GRATIS
selezionando l'opzione Corriere Veloce in fase di ordine.
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Preface…
Table of Contents…
Contributing Authors…
Part I Overview
1. Snake- and Spider-Venom-Derived Toxins as Lead Compounds for Drug Development
Philip Lazarovici
2. Analytics for Bioactivity Profiling of Complex Mixtures with a Focus on Venoms
Marija Mladic, Wilfried M.A. Niessen, Govert W. Somsen, and Jeroen Kool
Part II Toxins Purification and Production
3. Venom Collection from Spiders and Snakes: Voluntary and Involuntary Extractions (“Milking”) and Venom Gland Extractions
William K. Hayes, Gerad A. Fox, and David R. Nelsen
4. Production and Purification of Recombinant Toxins
Matan Geron
Part III Toxins Characterization
5. RNA-Sequencing of Snake Venom Glands
Khin Than Yee, Olga Vasieva, and Ponlapat Rojnuckarin
6. Exploring Toxin Evolution: Venom Protein Transcript Sequencing and Transcriptome-Guided High-Throughput Proteomics
Cassandra M. Modahl, Jordi Durban, and Stephen P. Mackessy
7. Three-Dimensional Structure Determination of Peptides using Solution Nuclear Magnetic Resonance Spectroscopy
Christina I. Schroeder and K. Johan Rosengren
8. Determining the Structures of the Snake and Spider Toxins by X-Rays
Anwar Ullah, Rehana Masood, Zafar Hayat, and Ahmed Hafeez
9. MALDI-TOF Mass Spectrometric Profiling of Spider Venoms
Ondrej Šedo, Stano Pekár, and Zbynek Zdráhal
Part IV Characterization of Toxins Function
10. Methods for Evaluation of a Snake Venom Derived Disintegrin in Animal Models of Human Cancer
Stephen D. Swenson, Catalina Silva-Hirschberg, and Francis S. Markland
11. Cell-Based Adhesion Assays for Isolation of Snake Venom's Integrin Antagonists
Philip Lazarovici, Cezary Marcinkiewicz, and Peter I. Lelkes
12. Using C. elegans to Study the Effects of Toxins in Sensory Ion Channels In Vivo
Valeria Vásquez
13. Measurements of Cell Death Induced by Snake and Spider’s Venoms and Derived Toxins
Yossi Maatuf, Avi Priel and Philip Lazarovici
14. Using Toxins in Brain Slice Recordings
Alexey Bingor and Rami Yaka
15. High-Throughput Calcium Imaging Screen of Toxins’ Function in Dissociated Sensory Neurons
Yossi Maatuf and Avi Priel
16. Synthesizing and Expressing Native Ion Channels
Shana L. Geffeney and Charles T. Hanifin
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