Part I. Introduction: 1. The neurobiology and aetiology of primary schizophrenia: current status Matcheri S. Keshavan and Ripu D. Jindal; 2. The concept of organicity and its application to schizophrenia Perminder S. Sachdev; 3. Secondary hallucinations Mark Walterfang, Ramon Mocellin, David Copolov and Dennis Velakoulis; Part II. The Neurology of Schizophrenia: 4. The neurologic examination in schizophrenia Richard D. Sanders and Matcheri S. Keshavan; 5. Functional neuroimaging in schizophrenia Serge A. Mitelman, Jane Zhang and Monte S. Buchsbaum; Part III. Organic Syndromes of Schizophrenia; Section 1. Epilepsy and Schizophrenia: 6. Schizophrenia-like psychosis and epilepsy Perminder S. Sachdev; 7. Understanding the pathophysiology of schizophrenia through the looking glass of forced normalization Ennapadam S. Krishnamoorthy and Seethalakshmi Ramanathan; Section 2. Drugs and Schizophrenia-like Psychosis: 8. Substance-induced psychosis: an overview Jagadisha Thirthalli, Vivek Benegal and Bangalore N. Gangadhar; 9. Stimulants and psychosis Nash N. Boutros, Matt Galloway and Eric M. Pihlgren; 10. The psychotomimetic effects of PCP, LSD and Ecstasy: pharmacological models of schizophrenia? Vibeke S. Catts and Stanley V. Catts; 11. Schizophrenia secondary to cannabis use Wayne Hall and Louisa Degenhardt; 12. Toxic psychosis Rajeev Kumar and Jeffrey C. L. Looi; Section 3. Other Neurological Disorders: 13. Schizophrenia-like psychosis and traumatic brain injury (TBI) Perminder S. Sachdev; 14. Cerebrovascular disease and psychosis Osvaldo P. Almeida and Sergio E. Starkstein; 15. Neurodegenerative disorders (Alzheimer's disease, frontotemporal dementia) and schizophrenia-like psychosis Nicola T. Lautenschlager and Alexander F. Kurz; 16. Storage disorders and psychosis Mark Walterfang and Dennis Velakoulis; 17. Mitochondrial disorders and psychosis Dennis Velakoulis and Mark Walterfang; 18. Psychosis associated with leukodystrophies Patricia I. Rosebush, Rebecca Anglin and Michael Mazurek; 19. Normal pressure hydrocephalus Julian Trollor; 20. Brain tumours Malcolm Hopwood and Lyn-May Lim; 21. Demyelinating disease and psychosis Anthony Feinstein; Section 4. Systemic Disorders: 22. Infection and schizophrenia Alan S. Brown and Ezra S. Susser; Section 5. Genetic Disorders Related to SLP: 23. The status of genetic investigations of schizophrenia Bryan Mowry; 24. Velocardiofacial Syndrome (Chromosome 22q11.2 Deletion Syndrome) as a model of schizophrenia Vandana Shashi and Margaret N. Berry; 25. Psychosis in Prader-Willi Syndrome Stewart L. Einfeld, Sophie Kavanagh, Arabella Smith and Bruce J. Tonge; 26. Friedrich's Ataxia and schizophrenia-type psychosis Perminder S. Sachdev; 27. Wilson's disease Edward C. Lauterbach and Leslie Lester-Burns; 28. Huntington's disease and related disorders and their association with schizophrenia-like psychosis Perminder S. Sachdev; 29. Fahr's disease and psychosis Kim Burns and Henry Brodaty; Part IV. Related Concepts: 30. The Charles Bonnet Syndrome William Burke; 31. Acute brief psychosis – an organic syndrome? Anand K. Pandurangi; Part V. Treatment: 32. Drug treatment of secondary schizophrenia Michael D. Jibson and Rajiv Tandon; 33. Non-pharmacological interventions in secondary schizophrenia David J. Kavanagh, Jennifer M. Connolly and Kim T. Mueser.