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duscher dominik (curatore); shiffman melvin a. (curatore) - regenerative medicine and plastic surgery

Regenerative Medicine and Plastic Surgery Skin and Soft Tissue, Bone, Cartilage, Muscle, Tendon and Nerves

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Dettagli

Genere:Libro
Lingua: Inglese
Editore:

Springer

Pubblicazione: 12/2020
Edizione: 1st ed. 2019





Trama

This book presents the latest advances in the field of regenerative medicine in plastic surgery. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner.
The first part introduces readers to essential principles of skin and soft tissue regeneration, e.g. the possibility of using mesenchymal stem cells for wound healing. Since bone serves as a supportive tissue in most of the body, bone regeneration is an important aspect of regenerative medicine; accordingly, the second part discusses the novel bone implants, activated bone grafts and bone tissue engineering. The book’s third part, focusing on cartilage regeneration, includes chapters on e.g. stem cells and ear regeneration. In turn, part four addresses muscle and tendon regeneration: from tendon to bone and tendon to muscle, as well as aging in the realm of muscle regeneration. Lastly, part five highlights nerve regeneration, deepening surgeons’ knowledge to help them successfully treat injuries to the peripheral neural system. 
Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties.

"With beautiful clinical images and artwork, this book will be a central companion to both practicing plastic surgeons who wish to remain abreast of oncoming technologic advances and regenerative medicine researchers who wish to understand the current state of the art of surgical reconstruction."
- Geoffrey C. Gurtner, MD, FACS
Johnson and Johnson Distinguished Professor of Surgery
Professor (by courtesy) of Bioengineering and Materials Science
Inaugural Vice Chairman of Surgery for Innovation
Stanford University School of Medicine





Sommario

PART 1: SKIN AND SOFT TISSUE REGENERATION
1. Induction of the Fetal Scarless Phenotype in Adult Wounds: Impossible?
2. Scar Treatment and Prevention: Know Thine Enemy
3. Challenges and Opportunities in Drug Delivery and Wound Healing
4. Harvesting, Processing and Injection of Lipoaspirate for Soft Tissue Reconstruction - Details Make the Difference
5. Adipose Tissue Complex (ATC):  Cellular & Biocellular Uses of Stem/Stromal Cells & Matrix in Cosmetic Plastic, Reconstructive Surgery & Regenerative Medicine
6. Preparation, Characterization, and Clinical Implications of Human Decellularized Adipose Tissue Extracellular Matrix
7. Mesenchymal Cells that Support Human Skin Regeneration
8. Stem Cells and Burn
9. Skin Tissue Engineering Advances in Severe Burns: Review and Therapeutic Applications
10. Skin Substitutes for Burn Wounds
11. Wnt Signaling During Cutaneous Wound Healing
12. Drug Delivery Advances for the Regeneration of Aged Skin
PART 2: BONE REGENERATION
13. Innovative Scaffold Solution for Bone Regeneration Made of Beta-Tricalcium Phosphate Granules, Autologous Fibrin Fold and Peripheral Blood Stem Cells
14. Ordinary and Activated Bone Substitutes
15. Absorbable Bone Substitute Materials Based on Calcium Sulfate as Triggers for Osteoinduction and Osteoconduction
16. Perivascular Progenitor Cells for Bone Regeneration
17. Bone Repair and Regeneration is Regulated by the Wnt Signaling Pathway
PART 3: CARTILAGE REGENERATION
18. Cartilage Tissue Engineering: Role of Mesenchymal Stem Cells, Growth Factors and Scaffolds
19. Sox9 Potentiates BMP2-induced Chondrogenic Differentiation and Inhibits BMP2-induced Osteogenic Differentiation
20. Stem Cells and Ear Regeneration
PART 4: MUSCLE AND TENDON REGENERATION
21. Muscle Fiber Regeneration in Long Term Denervated Muscles. Basics and Clinical Perspectives
22. Rejuvenating Stem Cells to Restore Muscle Regeneration in Aging
23. Silk Fibroin-Decorin Engineered Biologics to Repair Musculofascial Defects
24. Skeletal Muscle Restoration Following Volumetric Muscle Loss: the Therapeutic Effects of a Biologic Surgical Mesh
25. Principles of Tendon Regeneration
26. Stem Cells and Tendon Regeneration
27. Cell Therapies for Tendon: Treatments and Regenerative Medicine
PART 5: NERVE REGENERATION
28. The present and future for peripheral nerve regeneration
29. The Regeneration of Peripheral Nerves Depends on Repair Schwann Cells
30. Adipose-derived Stem Cells (ASCs) for Peripheral Nerve Regeneration
31. Direct Reprogramming Somatic Cells into Functional Neurons: A New Approach to Engineering Neural Tissue in Vitro and in Vivo




Autore

Dr. Dominik Duscher MD, PhD, is the director of the Division of Experimental Plastic Surgery at Technical University of Munich. He holds a doctorate of medicine and a research doctorate focusing on Stem Cell Biology and Regenerative Medicine. After his medical education in Vienna (Medical University of Vienna), London (University College London) and Boston (Harvard Medical School) he graduated from a postdoctoral fellowship in Stem Cell Biology and Regenerative Medicine at Stanford University. For his research he received the Stanford University biomaterial research prize, and scholarships from the American Austrian Foundation and the Austrian Science Fund, among other distinctions. Dr. Duscher holds multiple patents, published more than 100 peer reviewed publications and authored more than 100 conference presentations. Dominik Duscher is the General Secretary of the European Plastic Surgery Research Council. He further acts as the Research Coordinator of the Microsurgical Education Center of the Kepler University Hospital Linz and the Young Forum of the Austrian Society for Surgery of the Hand.

Dr. Melvin A. Shiffman
, MD, JD, FCLM, received his MD from Northwestern University School of Medicine in 1957 and completed his residency in general surgery in 1964 at the Veterans Administration Hospital, Long Beach, California. Since then he has been continuously involved in oncologic surgery, reconstruction, and cosmetic surgery. In 2002, Dr. Shiffman became Chair of the Section of Surgery at Tustin Hospital and Medical Center and in 2009-10 he served as President of the American College of Legal Medicine. He is Editor Emeritus of the American Journal of Cosmetic Surgery, a member of the Scientific Committee of the American Journal of Aesthetic Medicine, and an examiner for the International Board of Cosmetic Surgery. He is also a former Editor-in-Chief of both the American Journal of Cosmetic Surgery and the International Journal of Cosmetic Surgery. Dr. Shiffman is the recipient of many honors and is a fellow of various colleges and societies. He has published 320 articles, authored or edited 50 books, and written more than 210 book chapters.












Altre Informazioni

ISBN:

9783030199647

Condizione: Nuovo
Dimensioni: 254 x 178 mm Ø 1109 gr
Formato: Brossura
Illustration Notes:XXIV, 472 p. 108 illus., 97 illus. in color.
Pagine Arabe: 472
Pagine Romane: xxiv


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